US Physiological Saline Market Size and Forecasts (2020-2030)

US Physiological Saline Market Size and Forecasts (2020 – 2030), Regional Share, Trends, and Growth Opportunity Analysis Report Coverage: By Type (Normal Saline, Hypertonic Saline, Hypotonic Saline, and Balanced Saline), Packaging Type (Flexible Bags, Plastic Bottles, and Glass Bottles), Application (Intravenous, Ophthalmology, Wound Care, Endoscopy, Skin Abrasion, and Others), Route of Administration (Intravenous and Topical), and End User (Hospitals, Specialty Clinics, Ambulatory Surgical Centers, Homecare, and Others)

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Description

The physiological saline market was valued at US$ 2.412 billion in 2022 and is projected to reach US$ 3.910 billion by 2030; it is estimated to register a CAGR of 6.2% from 2022 to 2030. The rising prevalence of serious illnesses, fluid electrolyte disorders, and surging demand for fluid electrolytes in the elderly population are among the factors contributing to the growing physiological saline market size. However, the adverse effects of rapid isotonic saline infusion hinder the growth of the physiological saline market.

A physiological saline solution is composed of isotonic salt solutions with the same pH. An example of a physiological saline solution is Ringer’s solution, composed of sodium chloride (NaCl), sodium bicarbonate, and potassium chloride solution. The physician recommends the physiological solution in case of dehydration, fluid imbalances, and many more clinical abnormalities among the patients.

Market Opportunity

Rapid Sample Transportation Using Low-Cost Saline Solutions

A less expensive and readily available saline solution can transport testing samples, enabling more effective, safe, long-distance transportation of samples to diagnostic labs. A readily available saline solution such as “Phosphate Buffered Saline,” a simple salt solution commonly available in hospitals and clinical laboratories, was used as a transport medium for coronavirus-contaminated specimens; the saline could keep the samples stable for up to 18 hours. During the COVID-19 pandemic, a shortage of viral transport media posed a major challenge in transporting specimens obtained from COVID-19 patients to diagnostics and testing labs, resulting in an upsurge in demand for sterile saline solutions. As a result, researchers recommended using inexpensive and commonly available salt solutions, such as phosphate-buffered saline solutions, for transportation. Therefore, the rising awareness of less expensive and readily available saline solutions and their use in transporting medical specimens will likely provide opportunities to the US physiological saline market during 2022–2030.

Segmental Analysis

Type-Based Insights

By type, the US physiological saline market is segmented into normal saline, hypertonic saline, hypotonic saline, and balanced saline. The normal saline segment held the largest market share in 2022, and the same segment is anticipated to register the highest CAGR during 2022–2030. Normal saline (NS) comprises a sterile salt solution used for short-term fluid replacement, as it helps restore electrolyte/salt levels in the body. It is a 0.9% sodium chloride solution intended to treat dehydration and electrolyte disturbances among people. NS is a cornerstone of intravenous solutions commonly used in clinical settings. It is suitable for both pediatric and adult patient populations. Primary indications for the use of NS solutions that are approved by the Food and Drug Administration (FDA) are as follows:

• Extracellular fluid replacement to treat dehydration, hypovolemia, hemorrhage, sepsis, etc.

• Treatment of metabolic alkalosis in the presence of fluid loss

• Mild sodium depletion

Further, NS can only be administered through intravenous access, and normal saline management requires evaluating the patient’s health status. Pharmacists need to monitor the implementation of IV fluids while installing and recommending orders based on the patient’s clinical situation with proper counseling to the nursing department in the hospital regarding dosage and administration.

Packaging Type-Based Insights

The US physiological saline market, by packaging type, is segmented into flexible bags, plastic bottles, and glass bottles. The plastic bottles segment held a larger market share in 2022, and the flexible bag segment is anticipated to register the highest CAGR during the forecast period. Sodium chloride (NaCl) USP solutions for injections are sterile and nonpyrogenic. They are parenteral solutions containing various NaCl concentrations in water for injection (WFI) intended for intravenous (IV) administration. Further, the flexible container is fabricated from a specially formulated polyvinyl chloride. However, solutions coming in contact with plastic containers might leach out certain chemical components from the plastic in very small amounts. Further, biological testing proves effective in supporting the safety of plastic container materials. Therefore, the plastic bottles segment is expected to account for the smallest share of the physiological saline market during the forecast period.

Application-Based Insights

By application, the US physiological saline market is segmented as intravenous, ophthalmology, wound care, endoscopy, skin abrasion, and others. The intravenous segment held a larger market share in 2022, and the same segment is anticipated to register the highest CAGR during the forecast period. Intravenous (IV) saline solutions are formulated to prevent or treat dehydration. Physicians of all ages prescribe IV saline for people who are injured, sick, dehydrated, or undergoing surgery. Saline IV bags provide a rapid, targeted solution to replenish fluids and relieve symptoms.

Furthermore, a combination of sterile water and sodium chloride, or salt and normal saline IVs, helps restore fluid balance and hydrate tissues among patients. IV saline is commonly administered to patient’s bloodstreams when they require hydration. It is suitable for people with allergies or sensitivities to specific medications.

Various companies are producing innovative products related to IV saline; for example, Fresenius Kabi USA offers “freeflex” and “freeflex+ IV bags.” These products also provide leak prevention, sterility protection, and needle-stick prevention.

Route of Administration-Based Insights

The US physiological saline market, by route of administration, is bifurcated into intravenous and topical. The intravenous segment held a larger market share in 2022, and the same segment is anticipated to register the highest CAGR during the forecast period. IV saline solutions are specially formulated liquids that are injected into a vein to prevent and treat dehydration. Also, these IV fluids are utilized among people of all ages suffering from sickness, injury, dehydration, etc. The IV saline solution is a simple, safe, and common procedure with a low risk of complications. Also, fluid resuscitation is a vital component for managing acutely ill patients, and normal saline is considered the most widely used IV fluid for seriously ill or injured patients. Being a common, simple, and safe procedure, patients administered via the IV route may feel relief quickly.

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According to our new research study on “US Physiological Saline Market Size and Forecast to 2030 –Country Analysis – by Type, Packaging Type, Route of Administration, and End User,” the market is expected to grow from US$ 2.412 billion in 2022 to US$ 3.910 billion by 2030; it is estimated to record a CAGR 6.2% during 2022–2030. Factors like the rising prevalence of serious illnesses, fluid electrolyte disorders, and surging demand for fluid electrolytes in the elderly drive the US physiological saline market growth. However, the adverse effects of rapid isotonic saline infusion restrict the market’s growth.

A physiological saline solution consists of isotonic salt solutions with the same pH. For example, the Ringer’s solution is composed of a mixture of sodium chloride (NaCl), sodium bicarbonate, and potassium chloride. Physicians recommend the physiological solution in case of dehydration, fluid imbalances, and many more clinical abnormalities.

Future Trend

Large-Scale Saline Solution Requirements in Hospital Settings

According to a report published by the Royal Society of Chemistry, using saline solution to wash red blood cells (RBCs) and treat critically ill patients is a common practice in hospitals. Clinical research groups have reviewed the safety of using physiological saline (0.9% NaCl) in different clinical settings and suggested that saline solution is one of the safest techniques in hospital settings. For example, in transfusion medicine, saline solution is used for washing cells and salvaging procedures in cases of apheresis and the resuscitation of patients with blood or fluid loss. Washing of RBCs requires 1–2 L of sterile saline solution. In the apheresis procedure, saline solution is used in therapeutic plasma exchange procedures and intra-operative cell salvaging to wash RBCs. Therefore, the multifaceted application of physiological saline on large scales in hospital settings will likely emerge as a new trend in the US physiological saline market.

Packaging Type-Based Insights

The US physiological saline market, by packaging type, is segmented into flexible bags, plastic bottles, and glass bottles. The plastic bottles segment held a larger market share in 2022, and the flexible bag segment is anticipated to register the highest CAGR during the forecast period. Sodium chloride (NaCl) USP solutions for injections are sterile and nonpyrogenic. They are parenteral solutions containing various NaCl concentrations in water for injection (WFI) intended for intravenous (IV) administration. Further, the flexible container is fabricated from a specially formulated polyvinyl chloride. However, solutions in contact with plastic containers might leak certain chemical components from the plastic in very small amounts. Further, biological testing proves effective in supporting the safety of plastic container materials. Therefore, the plastic bottles segment is expected to account for the smallest share of the physiological saline market during the forecast period.

Application-Based Insights

By application, the US physiological saline market is segmented as intravenous, ophthalmology, wound care, endoscopy, skin abrasion, and others. The intravenous segment held a larger market share in 2022 and is anticipated to register the highest CAGR during the forecast period. Intravenous (IV) saline solutions are formulated to prevent or treat dehydration. Physicians of all ages prescribe IV saline for injured, sick, dehydrated, or undergoing surgery. Saline IV bags provide a rapid, targeted solution to replenish fluids and relieve symptoms.

Furthermore, a combination of sterile water and sodium chloride, or salt and normal saline IVs, helps restore fluid balance and hydrate tissues among patients. IV saline is commonly administered to patient’s bloodstreams when they require hydration. It is suitable for people with allergies or sensitivities to specific medications.

Various companies are producing innovative products related to IV saline; for example, Fresenius Kabi USA offers “freeflex” and “freeflex+ IV bags.” These products also provide leak prevention, sterility protection, and needle-stick prevention.

Fresenius Kabi AG, Merck KGaA, AdipoGen Life Sciences Inc, Enzo Life Sciences Inc, ICU Medical Inc, Grifols SA, Geno Technology Inc, B Braun Medical Inc, Pfizer Inc, and Ward’s Science are among the key companies operating in the US physiological saline market. Leading players adopt strategies such as launching new products, expanding and diversifying their market presence, and expanding new customer base to tap prevailing business opportunities.

o Save and reduce time carrying out entry-level research by identifying the growth, size, leading players and segments in the US physiological saline market.
o Highlights key business priorities in order to assist companies to realign their business strategies.
o The key findings and recommendations highlight crucial progressive industry trends in the global US physiological saline market, thereby allowing players across the value chain to develop effective long-term strategies.
o Develop/modify business expansion plans by using substantial growth offering developed and emerging markets.
o Scrutinize in-depth country market trends and outlook coupled with the factors driving the market, as well as those hindering it.
o Enhance the decision-making process by understanding the strategies that underpin security interest with respect to client products, segmentation, pricing and distribution.

TABLE OF CONTENTS

1. Introduction 13
1.1 The Research Team Report Guidance. 13
1.2 Market Segmentation. 14
2. Executive Summary 16
3. Research Methodology 17
3.1 Coverage. 19
3.2 Secondary Research. 19
3.3 Primary Research. 20
4. US Physiological Saline Market Landscape 21
4.1 Overview. 21
4.2 PEST Analysis. 22
4.2.1 US PEST Analysis. 22
4.3 Supply Chain Analysis. 22
5. US Physiological Saline Market – Key Industry Dynamics 25
5.1 Key Market Drivers. 26
5.1.1 Rising Prevalence of Serious Illnesses and Fluid Electrolytes Disorders. 26
5.2 Surging Demand for Fluid Electrolytes in Aging Population. 26
5.3 Key Market Restraints: 27
5.3.1 Adverse Effects of Rapid Isotonic Saline Infusion. 27
5.4 Key Market Opportunities: 27
5.4.1 Less Expensive Saline Solution Can Improve Speed and Transport 27
5.5 Future Trends. 28
5.5.1 Large-Scale Saline Solution Requirements in Hospital Settings. 28
5.6 Impact Analysis: 29
6. US Physiological Saline Market – Market Analysis 30
6.1 US Physiological Saline Market Revenue (US$ Mn), 2020 – 2030. 30
7. US Physiological Saline Market – Revenue and Forecast to 2030 – by Type 32
7.1 Overview. 32
7.2 US Physiological Saline Market Revenue Share, by Type 2022 & 2030 (%) 32
7.3 Normal Saline. 33
7.3.1 Overview. 33
7.3.2 Normal Saline: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 33
7.4 Hypertonic Saline. 35
7.4.1 Overview. 35
7.4.2 Hypertonic Saline: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 35
7.5 Hypotonic Saline. 37
7.5.1 Overview. 37
7.5.2 Hypotonic Saline: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 37
7.6 Balanced Saline Solution. 39
7.6.1 Overview. 39
7.6.2 Balanced Saline Solution: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 39
8. US Physiological Saline Market – Revenue and Forecast to 2030 – by Packaging Type 41
8.1 Overview. 41
8.2 US Physiological Saline Market Revenue Share, by Packaging Type 2022 & 2030 (%) 41
8.3 Flexible Bags. 42
8.3.1 Overview. 42
8.3.2 Flexible Bags: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 42
8.4 Plastic Bottles. 44
8.4.1 Overview. 44
8.4.2 Plastic Bottles: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 44
8.5 Glass Bottles. 46
8.5.1 Overview. 46
8.5.2 Glass Bottles: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 46
9. US Physiological Saline Market – Revenue and Forecast to 2030 – by Application 48
9.1 Overview. 48
9.2 US Physiological Saline Market Revenue Share, by Application 2022 & 2030 (%) 48
9.3 Intravenous. 49
9.3.1 Overview. 49
9.3.2 Intravenous: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 49
9.4 Ophthalmology. 51
9.4.1 Overview. 51
9.4.2 Ophthalmology: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 51
9.5 Wound Care. 53
9.5.1 Overview. 53
9.5.2 Wound Care: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 53
9.6 Endoscopy. 55
9.6.1 Overview. 55
9.6.2 Endoscopy: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 55
9.7 Skin Abrasion. 56
9.7.1 Overview. 56
9.7.2 Skin Abrasion: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 56
9.8 Others. 57
9.8.1 Overview. 57
9.8.2 Others: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 57
10. US Physiological Saline Market – Revenue and Forecast to 2030 – by Route of Administration 58
10.1 Overview. 58
10.2 US Physiological Saline Market Revenue Share, by Route of Administration 2022 & 2030 (%) 58
10.3 Intravenous. 59
10.3.1 Overview. 59
10.3.2 Intravenous: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 59
10.4 Topical 60
10.4.1 Overview. 60
10.4.2 Topical: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 60
11. US Physiological Saline Market – Revenue and Forecast to 2030 – by End User 62
11.1 Overview. 62
11.2 US Physiological Saline Market Revenue Share, by End User 2022 & 2030 (%) 62
11.3 Hospitals. 63
11.3.1 Overview. 63
11.3.2 Hospitals: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 63
11.4 Specialty Clinics. 64
11.4.1 Overview. 64
11.4.2 Specialty Clinics: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 64
11.5 Ambulatory Surgical Centers. 65
11.5.1 Overview. 65
11.5.2 Ambulatory Surgical Centers: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 65
11.6 Homecare. 66
11.6.1 Overview. 66
11.6.2 Homecare: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 66
11.7 Others. 67
11.7.1 Overview. 67
11.7.2 Others: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 67
12. Company Profiles 68
12.1 Fresenius Kabi AG. 68
12.1.1 Key Facts. 68
12.1.2 Business Description. 68
12.1.3 Products and Services. 69
12.1.4 Financial Overview. 69
12.1.5 SWOT Analysis. 70
12.1.6 Key Developments. 70
12.2 Merck KGaA. 71
12.2.1 Key Facts. 71
12.2.2 Business Description. 71
12.2.3 Products and Services. 72
12.2.4 Financial Overview. 74
12.2.5 SWOT Analysis. 77
12.2.6 Key Developments. 77
12.3 AdipoGen Life Sciences Inc. 78
12.3.1 Key Facts. 78
12.3.2 Business Description. 78
12.3.3 Products and Services. 79
12.3.4 Financial Overview. 82
12.3.5 SWOT Analysis. 82
12.3.6 Key Developments. 82
12.4 Enzo Life Sciences Inc. 83
12.4.1 Key Facts. 83
12.4.2 Business Description. 83
12.4.3 Products and Services. 84
12.4.4 Financial Overview. 86
12.4.5 SWOT Analysis. 87
12.4.6 Key Developments. 87
12.5 ICU Medical Inc. 88
12.5.1 Key Facts. 88
12.5.2 Business Description. 88
12.5.3 Products and Services. 89
12.5.4 Financial Overview. 90
12.5.5 SWOT Analysis. 92
12.5.6 Key Developments. 93
12.6 Grifols SA. 94
12.6.1 Key Facts. 94
12.6.2 Business Description. 94
12.6.3 Products and Services. 95
12.6.4 Financial Overview. 97
12.6.5 SWOT Analysis. 99
12.6.6 Key Developments. 100
12.7 Geno Technology Inc. 101
12.7.1 Key Facts. 101
12.7.2 Business Description. 101
12.7.3 Products and Services. 102
12.7.4 Financial Overview. 105
12.7.5 SWOT Analysis. 105
12.7.6 Key Developments. 106
12.8 B Braun Medical Inc. 107
12.8.1 Key Facts. 107
12.8.2 Business Description. 107
12.8.3 Products and Services. 108
12.8.4 Financial Overview. 111
12.8.5 SWOT Analysis. 111
12.8.6 Key Developments. 112
12.9 Pfizer Inc. 113
12.9.1 Key Facts. 113
12.9.2 Business Description. 113
12.9.3 Products and Services. 114
12.9.4 Financial Overview. 115
12.9.5 SWOT Analysis. 117
12.9.6 Key Developments. 118
12.10 Ward’s Science. 119
12.10.1 Key Facts. 119
12.10.2 Business Description. 119
12.10.3 Products and Services. 120
12.10.4 Financial Overview. 127
12.10.5 SWOT Analysis. 128
12.10.6 Key Developments. 128
13. Appendix 129
13.1 About Us. 129
13.2 Glossary of Terms. 131

LIST OF TABLES

Table 1. US Physiological Saline Market Segmentation. 14
Table 2. Normal Saline 2020-2030 (US$ Mn) 34
Table 3. Normal Saline 2020-2030 (US$ Mn) 36
Table 4. Hypotonic Saline 2020-2030 (US$ Mn) 38
Table 5. Balanced Saline Solution (BSS) 2020-2030 (US$ Mn) 40
Table 6. Flexible Bags 2020-2030 (US$ Mn) 43
Table 7. Plastic Bottles 2020-2030 (US$ Mn) 45
Table 8. Glass Bottles 2020-2030 (US$ Mn) 47
Table 9. Topical 2020-2030 (US$ Mn) 61
Table 10. Glossary of Terms, US Physiological Saline Market 131

LIST OF FIGURES

Figure 1. US Physiological Saline Market Segmentation, By Country. 15
Figure 2. Key Insights. 16
Figure 3. US – PEST Analysis. 22
Figure 4. US Physiological Saline Market – Key Industry Dynamics. 25
Figure 5. Impact Analysis of Drivers and Restraints. 29
Figure 6. US Physiological Saline Market Revenue (US$ Mn), 2020 – 2030. 31
Figure 7. US Physiological Saline Market Revenue Share, by Type 2022 & 2030 (%) 32
Figure 8. Normal Saline: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 34
Figure 9. Hypertonic Saline: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 36
Figure 10. Hypertonic Saline: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 38
Figure 11. Balanced Saline Solution: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 40
Figure 12. US Physiological Saline Market Revenue Share, by Packaging Type 2022 & 2030 (%) 41
Figure 13. Flexible Bags: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 43
Figure 14. Plastic Bottles: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 45
Figure 15. Glass Bottles: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 47
Figure 16. US Physiological Saline Market Revenue Share, by Application 2022 & 2030 (%) 48
Figure 17. Intravenous: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 50
Figure 18. Ophthalmology: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 52
Figure 19. Wound Care: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 54
Figure 20. Endoscopy: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 55
Figure 21. Skin Abrasion: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 56
Figure 22. Others: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 57
Figure 23. US Physiological Saline Market Revenue Share, by Route of Administration 2022 & 2030 (%) 58
Figure 24. Intravenous: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 59
Figure 25. Topical: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 60
Figure 26. US Physiological Saline Market Revenue Share, by End User 2022 & 2030 (%) 62
Figure 27. Hospitals: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 63
Figure 28. Specialty Clinics: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 64
Figure 29. Ambulatory Surgical Centers: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 65
Figure 30. Homecare: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 66
Figure 31. Others: US Physiological Saline Market – Revenue and Forecast to 2030 (US$ Million) 67

The List of Companies – US Physiological Saline Market
o Fresenius Kabi AG      
o Merck KGaA                 
o AdipoGen Life Sciences Inc     
o Enzo Life Sciences Inc               
o ICU Medical Inc           
o Grifols SA       
o Geno Technology Inc                
o B Braun Medical Inc   
o Pfizer Inc        
o Ward’s Science

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