South & Central America Upstream Bioprocessing Market Forecast to 2030
South & Central America Upstream Bioprocessing Market Forecast to 2030 – Regional analysis – by Product Type (Bioreactors/Fermenters, Cell Culture, Filters, Bags and Containers, and Others), Workflow (Media Preparation, Cell Culture, and Cell Separation), Usage Type (Single-use and Multi-use), and Mode (In-house and Outsourced)
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Description
Technological Advancements Fuel South & Central America Upstream Bioprocessing Market.
The upstream bioprocessing market is experiencing a wave of technological advancements, presenting considerable industry opportunities. These advancements include innovative developments in cell culture systems, bioreactor design, process monitoring, and control, as well as the integration of automation and digitalization. In September 2023, Repligen Corporation and Sartorius introduced an integrated bioreactor system. Repligen’s XCell Alternating Tangential Flow (ATF) upstream intensification technology has been integrated into the Sartorius Biostat stirred-tank reactor (STR). This bioreactor technology is designed to make the application of N perfusion and intensified seed train easier for biopharmaceutical firms. An embedded XCell ATF hardware and software module that combines integrated process analytical technologies with predefined advanced control recipes is incorporated into Biostat STR. This module is intended to simplify the management of cell growth and enhance cell retention in perfusion procedures, eliminating the need for a separate cell retention control tower. Such modern products feature enhanced process efficiency, scalability, and adaptability, which are crucial for meeting the evolving demands of biopharmaceutical production.
Advanced cell culture media formulations and next-generation bioreactor technologies are contributing to the optimization of upstream bioprocessing, in turn, enabling higher product yields, improved product quality, and the efficient production of complex biologics. The ongoing integration of advanced analytics and real-time process monitoring is revolutionizing data-driven decision-making in bioprocessing, driving precision and process optimization opportunities. Progress in biotechnology also fosters the development of flexible and modular manufacturing platforms. Additionally, the convergence of machine learning, artificial intelligence, and predictive analytics is paving the way for predictive bioprocessing, thereby unlocking proactive process control, quality assurance, and cost optimization opportunities. Thus, technological advancements in upstream bioprocessing are reshaping the industry, presenting new avenues for innovation, efficiency, and adaptability.
South & Central America Upstream Bioprocessing Market Overview
The South & Central America upstream bioprocessing market is segmented into Brazil, Argentina, and the Rest of South & Central America. Recent technological advancements have had a direct impact on the economy of Brazil. Cost savings and higher work efficiencies achieved are cited as the major points attracting manufacturing companies to establish bases in South America.
South & Central America Upstream Bioprocessing Market Revenue and Forecast to 2030 (US$ Million)
South & Central America Upstream Bioprocessing Market Segmentation
The South & Central America upstream bioprocessing market is segmented based on product type, workflow, usage type, mode, and country. Based on product type, the South & Central America upstream bioprocessing market is segmented into bioreactors/fermenters, cell culture, filters, bags and containers, and others. The cell culture services held the largest market share in 2022.
Based on workflow, the South & Central America upstream bioprocessing market is categorized into media preparation, cell culture, and cell separation. The cell separation held the largest market share in 2022.
Based on usage type, the South & Central America upstream bioprocessing market is bifurcated into single-use and multi-use. The single-use held a larger market share in 2022
Based on mode, the South & Central America upstream bioprocessing market is bifurcated into in-house and outsourced. The outsourced held a larger market share in 2022.
Based on country, the South & Central America upstream bioprocessing market is segmented into Brazil, Argentina, and the Rest of South & Central America. Brazil dominated the South & Central America upstream bioprocessing market share in 2022.
Thermo Fisher Scientific Inc, Sartorius AG, Danaher Corp, Getinge AB, Merck KGaA, and Corning Inc are some of the leading companies operating in the South & Central America upstream bioprocessing market.
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According to the Research Team’ research, the South & Central America upstream bioprocessing market was valued at US$ 382.56 million in 2022 and is expected to reach US$ 981.89 million by 2030, registering a CAGR of 12.5% from 2022 to 2030. Increasing investments in R&D in biopharmaceutical industry and rapid growth of pharmaceutical and biotechnology industries are among the critical factors attributed to the South & Central America upstream bioprocessing market expansion.
Increasing investments in research and development (R&D) in the biopharmaceutical industry are likely to bring new trends into the upstream bioprocessing market in the coming years. In March 2020, Culture Biosciences announced securing the funds of US$ 15 million (€13.4 million) in the Series A investment round, citing the backing of new and existing venture capital backers. According to Culture Biosciences, the money has been used to treble the capacity of bioreactors as well as to develop more cloud-based software monitoring and development tools for biomanufacturing research and development. The company states that this investment will help scientists manage their whole R&D workflow via software applications, hence supporting the digitization of biomanufacturing R&D.
As R&D investments continue to surge, particularly in novel biologics, advanced therapies, and personalized medicine, there is a parallel emphasis on optimizing upstream bioprocessing technologies and methodologies. This trend is leading to the development of innovative bioreactor systems, cell culture media formulations, and process automation solutions to enhance the efficiency, scalability, and productivity of biopharmaceutical production operations. Furthermore, the focus on R&D investments favors the development of cutting-edge bioprocessing platforms that cater to the evolving landscape of biopharmaceuticals, including next-generation therapeutic modalities and biosimilars. Additionally, dedicating R&D funds for bioprocessing trends such as continuous bioprocessing and advanced analytics for process monitoring is expected to reshape the future of upstream bioprocessing, driving the adoption of state-of-the-art technologies and establishing new benchmarks for process performance, quality, and regulatory compliance.
On the contrary, stringent regulatory framework hampers the growth of South & Central America upstream bioprocessing market.
Based on product type, the South & Central America upstream bioprocessing market is segmented into bioreactors/fermenters, cell culture, filters, bags and containers, and others. The bioreactors/fermenters segment held 35.2% market share in 2022, amassing US$ 134.60 million. It is projected to garner US$ 342.96 million by 2030 to expand at 12.4% CAGR during 2022–2030.
Based on workflow, the South & Central America upstream bioprocessing market is segmented into media preparation, cell culture, and cell separation. The cell separation segment held 41.9% share of South & Central America upstream bioprocessing market in 2022, amassing US$ 160.27 million. It is projected to garner US$ 426.49 million by 2030 to expand at 13.0% CAGR during 2022–2030.
By usage type, the South & Central America upstream bioprocessing market is bifurcated into single-use and multi-use. The single-use segment held 54.3% share of South & Central America upstream bioprocessing market in 2022, amassing US$ 207.54 million. It is projected to garner US$ 542.00 million by 2030 to expand at 12.7% CAGR during 2022–2030.
In terms of mode, the South & Central America upstream bioprocessing market is bifurcated into In-house and outsourced. The In-house segment held 62.5% share of South & Central America upstream bioprocessing market in 2022, amassing US$ 239.23 million. It is projected to garner US$ 603.04 million by 2030 to expand at 12.3% CAGR during 2022–2030.
Based on country, the South & Central America upstream bioprocessing market has been categorized into Brazil, Argentina, and the Rest of South & Central America. Our regional analysis states that Brazil captured 65.3% share of South & Central America upstream bioprocessing market in 2022. It was assessed at US$ 249.89 million in 2022 and is likely to hit US$ 654.80 million by 2030, exhibiting a CAGR of 12.8% during 2022–2030.
Key players operating in the South & Central America upstream bioprocessing market are Thermo Fisher Scientific Inc, Sartorius AG, Danaher Corp, Getinge AB, Merck KGaA, and Corning Inc, among others.
In December 2023, Merck has acquired Erbi Biosystems, a Massachusetts-based company that developed the “Breez” 2 ml micro-bioreactor platform technology. Merck’s upstream therapeutic protein portfolio is boosted by the purchase, enabling it to promptly develop lab-scale protocols for scalable cell-based perfusion bioreactor processes with capacities ranging from 2 ml to 2000 l. Additionally, it offers opportunities for further study and advancement in cutting-edge modality applications, like cell therapies. In May 2023, Danaher Corp announced that it has merged its Pall portfolio under the Cytiva brand. The merger has enhanced customers’ access to bioprocess technologies and services. The merger will help the company offer biomanufacturers products and technologies across the full bioprocess spectrum, ranging from cell culture to drug products. All the products will be sold under the brand Cytiva. In addition, the merger has combined iCELLis, Kleenpak, Allegro, Supor, and Pegasus, in addition to ÄKTA, Amersham, B Sefia, Whatman, Xcellerex, Xuri, Biacore, FlexFactory, HyClone, and MabSelect.
o Highlights key business priorities in order to assist companies to realign their business strategies.
o The key findings and recommendations highlight crucial progressive industry trends in South & Central America upstream bioprocessing market, thereby allowing players across the value chain to develop effective long-term strategies.
o Develop/modify business expansion plans by using substantial growth offering developed and emerging markets.
o Scrutinize in-depth South & Central America market trends and outlook coupled with the factors driving the market, as well as those hindering it.
o Enhance the decision-making process by understanding the strategies that underpin security interest with respect to client products, segmentation, pricing, and distribution.
1. Introduction
1.1 The the Reporting Teams Research Report Guidance
1.2 Market Segmentation
2. Executive Summary
2.1 Key Insights
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. South & Central America Upstream Bioprocessing Market Landscape
4.1 Overview
4.2 PEST Analysis
5. South & Central America Upstream Bioprocessing Market Key Market Dynamics
5.1 Market Drivers
5.1.1 Commercial Use of Single-Use Bioreactors
5.1.2 Outsourcing of Biopharmaceutical Manufacturing
5.1.3 Rapid Growth of Pharmaceutical and Biotechnology Industries
5.2 Market Restraints
5.2.1 Stringent Regulatory Framework
5.3 Market Opportunities
5.3.1 Technological Advancements
5.4 Future Trends
5.4.1 Increasing Investments in R&D in Biopharmaceutical Industry
5.5 Impact of Drivers and Restraints:
6. Upstream Bioprocessing Market – South & Central America Analysis
7. South & Central America Upstream Bioprocessing Market Analysis – by Product Type
7.1 Bioreactors/Fermenters
7.1.1 Overview
7.1.2 Bioreactors/Fermenters: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
7.2 Cell Culture
7.2.1 Overview
7.2.2 Cell Culture: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
7.3 Filters
7.3.1 Overview
7.3.2 Filters: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
7.4 Bags and Containers
7.4.1 Overview
7.4.2 Bags and Containers: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
7.5 Others
7.5.1 Overview
7.5.2 Others: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
8. South & Central America Upstream Bioprocessing Market Analysis – by Workflow
8.1 Media Preparation
8.1.1 Overview
8.1.2 Media Preparation: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
8.2 Cell Culture
8.2.1 Overview
8.2.2 Cell Culture: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
8.3 Cell Separation
8.3.1 Overview
8.3.2 Cell Separation: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
9. South & Central America Upstream Bioprocessing Market Analysis – by Usage Type
9.1 Single-use
9.1.1 Overview
9.1.2 Single-use: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
9.2 Multi-use
9.2.1 Overview
9.2.2 Multi-use: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
10. South & Central America Upstream Bioprocessing Market Analysis – by Mode
10.1 In-house
10.1.1 Overview
10.1.2 In-house: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
10.2 Outsourced
10.2.1 Overview
10.2.2 Outsourced: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11. South & Central America Upstream Bioprocessing Market – Country Analysis
11.1 South & Central America Market Overview
11.1.1 South & Central America: Upstream Bioprocessing Market – Revenue and Forecast Analysis – by Country
11.1.1.1 South & Central America: Upstream Bioprocessing Market – Revenue and Forecast Analysis – by Country
11.1.1.2 Brazil
11.1.1.3 Brazil: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11.1.1.3.1 Brazil: Upstream Bioprocessing Market Breakdown, by Product Type
11.1.1.3.2 Brazil: Upstream Bioprocessing Market Breakdown, by Workflow
11.1.1.3.3 Brazil: Upstream Bioprocessing Market Breakdown, by Usage Type
11.1.1.3.4 Brazil: Upstream Bioprocessing Market Breakdown, by Mode
11.1.1.4 Argentina
11.1.1.5 Argentina: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11.1.1.5.1 Argentina: Upstream Bioprocessing Market Breakdown, by Product Type
11.1.1.5.2 Argentina: Upstream Bioprocessing Market Breakdown, by Workflow
11.1.1.5.3 Argentina: Upstream Bioprocessing Market Breakdown, by Usage Type
11.1.1.5.4 Argentina: Upstream Bioprocessing Market Breakdown, by Mode
11.1.1.6 Rest of South & Central America
11.1.1.7 Rest of South & Central America: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11.1.1.7.1 Rest of South & Central America: Upstream Bioprocessing Market Breakdown, by Product Type
11.1.1.7.2 Rest of South & Central America: Upstream Bioprocessing Market Breakdown, by Workflow
11.1.1.7.3 Rest of South & Central America: Upstream Bioprocessing Market Breakdown, by Usage Type
11.1.1.7.4 Rest of South & Central America: Upstream Bioprocessing Market Breakdown, by Mode
12. Industry Landscape
12.1 Overview
12.2 Growth Strategies in Upstream Bioprocessing Market
12.3 Organic Growth Strategies
12.3.1 Overview
12.4 Inorganic Growth Strategies
12.4.1 Overview
13. Company Profiles
13.1 Thermo Fisher Scientific Inc
13.1.1 Key Facts
13.1.2 Business Description
13.1.3 Products and Services
13.1.4 Financial Overview
13.1.5 SWOT Analysis
13.1.6 Key Developments
13.2 Sartorius AG
13.2.1 Key Facts
13.2.2 Business Description
13.2.3 Products and Services
13.2.4 Financial Overview
13.2.5 SWOT Analysis
13.2.6 Key Developments
13.3 Danaher Corp
13.3.1 Key Facts
13.3.2 Business Description
13.3.3 Products and Services
13.3.4 Financial Overview
13.3.5 SWOT Analysis
13.3.6 Key Developments
13.4 Getinge AB
13.4.1 Key Facts
13.4.2 Business Description
13.4.3 Products and Services
13.4.4 Financial Overview
13.4.5 SWOT Analysis
13.4.6 Key Developments
13.5 Merck KGaA
13.5.1 Key Facts
13.5.2 Business Description
13.5.3 Products and Services
13.5.4 Financial Overview
13.5.5 SWOT Analysis
13.5.6 Key Developments
13.6 Corning Inc
13.6.1 Key Facts
13.6.2 Business Description
13.6.3 Products and Services
13.6.4 Financial Overview
13.6.5 SWOT Analysis
13.6.6 Key Developments
14. Appendix
14.1 About The the Reporting Teams
14.2 Glossary of Terms
Table 1. Upstream Bioprocessing Market Segmentation
Table 2. Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 3. Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 4. Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 5. Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 6. South & Central America: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Country
Table 7. Brazil: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 8. Brazil: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 9. Brazil: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 10. Brazil: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 11. Argentina: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 12. Argentina: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 13. Argentina: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 14. Argentina: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 15. Rest of South & Central America: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 16. Rest of South & Central America: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 17. Rest of South & Central America: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 18. Rest of South & Central America: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 19. Recent Organic Growth Strategies in Upstream Bioprocessing Market
Table 20. Recent Inorganic Growth Strategies in the Upstream Bioprocessing Market
Table 21. Glossary of Terms, Upstream Bioprocessing Market
Figure 1. Upstream Bioprocessing Market Segmentation, by Country
Figure 2. PEST Analysis
Figure 3. Upstream Bioprocessing Market – Key Market Dynamics
Figure 4. Impact Analysis of Drivers and Restraints
Figure 5. Upstream Bioprocessing Market Revenue (US$ Million), 2020-2030
Figure 6. Upstream Bioprocessing Market Share (%) – by Product Type (2022 and 2030)
Figure 7. Bioreactors/Fermenters: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 8. Cell Culture: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 9. Filters: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 10. Bags and Containers: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 11. Others: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 12. Upstream Bioprocessing Market Share (%) – by Workflow (2022 and 2030)
Figure 13. Media Preparation: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 14. Cell Culture: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 15. Cell Separation: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 16. Upstream Bioprocessing Market Share (%) – by Usage Type (2022 and 2030)
Figure 17. Single-use: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 18. Multi-use: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 19. Upstream Bioprocessing Market Share (%) – by Mode (2022 and 2030)
Figure 20. In-house: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 21. Outsourced: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 22. South & Central America: Upstream Bioprocessing Market, by Key Country – Revenue (2022) (US$ Million)
Figure 23. South & Central America: Upstream Bioprocessing Market Breakdown, by Key Countries, 2022 and 2030 (%)
Figure 24. Brazil: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 25. Argentina: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 26. Rest of South & Central America: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 27. Growth Strategies in Upstream Bioprocessing Market
The List of Companies – South and Central America Upstream Bioprocessing Market
1. Thermo Fisher Scientific Inc
2. Sartorius AG
3. Danaher Corp
4. Getinge AB
5. Merck KGaA
6. Corning Inc.
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