North America Organoids Market Forecast to 2030

According to the research team’ research, the North America organoids market was valued at US$ 1,125.01 million in 2022 and is expected to reach US$ 5,359.72 million by 2030, registering a CAGR of 21.5% from 2022 to 2030. Increasing demand for tumor modeling and biobanking as well as growing adoption of personalized drugs are the critical factors attributed to the North America organoids market expansion.

Organoids are microscopic and self-organizing 3D structures grown from stem cells in vitro. They review various structural and functional characteristics of their in vivo counterpart organs. This multipurpose technology has led to several novel human cancer models. It is now possible to create indefinitely expanding organoids starting from the tumor tissue of individuals suffering from a range of carcinomas. Alternatively, CRISPR-based gene modification allows the engineering of organoid models of cancer by introducing any combination of cancer gene alterations to normal organoids. Tumor organoids, when combined with immune cells and fibroblasts, become a model for the cancer microenvironment enabling immune-oncology applications. Also, recent studies have proved that organoids have a place in personalized medicine approaches.

The constant progress in organoid technology has paved the way for tumors and patient-centric 3D cultures of cells isolated from tumor biopsies. Over the past few decades, organoids have been generated from diverse human cancers associated with breast, colon, pancreas, prostate, bladder, and liver. Studies involving these models help in providing key facts about these malignancies. Due to constant advancements in the current scenario, tumoroid lines are increasingly being passed in vitro, opening new paths for a range of downstream applications. Moreover, 3D-based cultures offer added advantages over conventional 2D cancer-derived cell lines. Further, recent research and development activities have specified that tumoroid culturing is highly effective in allowing the collection of various cancer subtypes from a large pool of patients. As organoids can be easily derived and expanded from single cancer cells, the adoption of organoids to mimic intratumor diversification in culture is increasing, which, in turn, is propelling the North America organoids market.

Companies have been developing innovative biobanks for storing several biological samples, including tumors. For instance, OrganoidBase (developed by Crown Bioscience) consists of 342 tumor organoid models derived from patient-derived xenograft (PDX) models [i.e., PDX-derived organoids (PDXOs)]. PDXOs offer detailed information on histopathology, IC50, genomic, and transcriptomic analysis data associated with drug response; it also has an additional 217 models from primary patient samples. These PDXO models have varied indications, with multiple models derived from over 20 organ and tissue types. Crown Biosciences commercializes organoids in a 3D in vitro model derived using IP-protected Hubrecht Organoid Technology (HUB) protocols. Thus, such innovations are driving the market growth.

On the contrary, issues related to incorporation of organoids into existing workflows and dearth of skilled professionals hampers the North America organoids market.

Based on organ type, the North America organoids market is segmented into intestine, liver, stomach, pancreas, lung, brain, kidney, and others. The intestine segment held 23.3% share of North America organoids market in 2022, amassing US$ 261.72 million. It is projected to garner US$ 1,224.22 million by 2030 to expand at 21.3% CAGR during 2022–2030.

Based on application, the North America organoids market is segmented into developmental biology disease, pathology of infectious disease, regenerative medicine, drug toxicity and efficacy testing, drug discovery and personalized medicine, and others. The developmental biology disease segment held 29.3% share of North America organoids market in 2022, amassing US$ 330.17 million. It is projected to garner US$ 1,647.09 million by 2030 to expand at 22.2% CAGR during 2022–2030.

Based on source, the North America organoids market is bifurcated into pluripotent stem cells and organ-specific adult stem cell. The pluripotent stem cells segment held 72.7% share of North America organoids market in 2022, amassing US$ 817.37 million. It is projected to garner US$ 4,016.63 million by 2030 to expand at 22.0% CAGR during 2022–2030.

Based on type, the North America organoids market is segmented into instruments, consumables, and services. The consumables segment held 58.8% share of North America organoids market in 2022, amassing US$ 661.17 million. It is projected to garner US$ 3,400.92 million by 2030 to expand at 22.7% CAGR during 2022–2030.

Based on country, the North America organoids market has been categorized into the US, Canada, and Mexico. Our regional analysis states that the US captured 80.0% share of North America organoids market in 2022. It was assessed at US$ 899.96 million in 2022 and is likely to hit US$ 4,350.03 million by 2028, exhibiting a CAGR of 21.8% during 2022–2030.

Key players operating in the North America organoids market are STEMCELL Technologies Inc, Cellesce Ltd, Organoid Therapeutics, 3Dnamics Inc, Thermo Fisher Scientific Inc, Merck KGaA, and InSphero, among others.

In August 2021, InSphero AG announced that it is making its proprietary, patented 96- and 384-microwell plates available to researchers, enabling them to access the same plate technology used in the company’s flagship, assay-ready 3D InSight Human Liver Microtissues. The plates, engineered specifically for 3D cultures of spheroids and organoids, are available via InSphero’s online R&D Solutions Store. In February 2023, the collaboration will integrate the Thermo Scientific Momentum workflow scheduling software with the Celltrio RoboCell cell line automation platform to address the unmet market need for high-throughput automated cell line culturing and maintenance.

1. Introduction
1.1 The Research Team Report Guidance
1.2 Market Segmentation
2. Executive Summary
2.1 North America Key Insights
2.2 North America Market Attractiveness
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. North America Organoids Market Landscape
4.1 Overview
4.2 North America PEST Analysis
5. North America Organoids Market – Key Industry Dynamics
5.1 Key Market Drivers:
5.1.1 Increasing Demand for Tumor Modeling and Biobanking
5.1.2 Growing Adoption of Personalized Drugs
5.1.3 Rising Focus on Developing Alternatives for Animal Testing Models
5.2 Key Market Restraints:
5.2.1 Issues Related to Incorporation of Organoids into Existing Workflows
5.2.2 Dearth of Skilled Professionals
5.3 Key Market Opportunities:
5.3.1 Focus on Drug Discovery Activities
5.4 Future Trends:
5.4.1 Combining Organoid with Organ-On-A-Chip
5.5 Impact Analysis:
6. Organoids Market – North America Market Analysis
6.1 North America Organoids Market Revenue (US$ Mn), 2022 – 2030
7. North America Organoids Market – Revenue and Forecast to 2030 – by Organ Type
7.1 Overview
7.2 North America Organoids Market Revenue Share, by Organ Type 2022 & 2030 (%)
7.3 Stomach
7.3.1 Overview
7.3.2 Stomach: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.4 Intestine
7.4.1 Overview
7.4.2 Intestine: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.4.3
7.5 Liver
7.5.1 Overview
7.5.2 Liver: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.6 Pancreas
7.6.1 Overview
7.6.2 Pancreas: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.7 Lung
7.7.1 Overview
7.7.2 Lung: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.8 Brain
7.8.1 Overview
7.8.2 Brain: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.9 Kidney
7.9.1 Overview
7.9.2 Kidney: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.10 Others
7.10.1 Overview
7.10.2 Others: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8. North America Organoids Market – Revenue and Forecast to 2030 – by Application
8.1 Overview
8.2 North America Organoids Market Revenue Share, by Application 2022 & 2030 (%)
8.3 Developmental Biology
8.3.1 Overview
8.3.2 Developmental Biology: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.4 Disease Pathology of Infectious Disease
8.4.1 Overview
8.4.2 Disease Pathology of Infectious Disease: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.5 Regenerative Medicine
8.5.1 Overview
8.5.2 Regenerative Medicine: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.6 Drug Toxicity and Efficacy Testing
8.6.1 Overview
8.6.2 Drug Toxicity and Efficacy Testing: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.7 Drug Discovery and Personalized Medicine
8.7.1 Overview
8.7.2 Drug Discovery and Personalized Medicine: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.8 Others
8.8.1 Overview
8.8.2 Others: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
9. North America Organoids Market – Revenue and Forecast to 2030 – by Source
9.1 Overview
9.2 North America Organoids Market Revenue Share, by Source 2022 & 2030 (%)
9.3 Pluripotent Stem Cells
9.3.1 Overview
9.3.2 Pluripotent Stem Cells: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
9.4 Organ-specific Adult Stem Cells
9.4.1 Overview
9.4.2 Organ-specific Adult Stem Cells: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
10. North America Organoids Market – Revenue and Forecast to 2030 – by Type
10.1 Overview
10.2 North America Organoids Market Revenue Share, by Type 2022 & 2030 (%)
10.3 Instruments
10.3.1 Overview
10.3.2 Instruments: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
10.4 Consumables
10.4.1 Overview
10.4.2 Consumables: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
10.5 Services
10.5.1 Overview
10.5.2 Services: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
11. North America Organoids Market – Country Analysis
11.1 North America: Overview
11.1.1 North America Organoids Market, by Country
11.1.1.1 US
11.1.1.1.1 Overview
11.1.1.1.2 US Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.1.1.1.3 US Organoids Market, by Organ Type
11.1.1.1.4 US Organoids Market, by Application
11.1.1.1.5 US Organoids Market, by Source
11.1.1.1.6 US Organoids Market, by Type
11.1.1.2 Canada
11.1.1.2.1 Overview
11.1.1.2.2 Canada Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.1.1.2.3 Canada Organoids Market, by Organ Type
11.1.1.2.4 Canada Organoids Market, by Application
11.1.1.2.5 Canada Organoids Market, by Source
11.1.1.2.6 Canada Organoids Market, by Type
11.1.1.3 Mexico
11.1.1.3.1 Overview
11.1.1.3.2 Mexico Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.1.1.3.3 Mexico Organoids Market, by Organ Type
11.1.1.3.4 Mexico Organoids Market, by Application
11.1.1.3.5 Mexico Organoids Market, by Source
11.1.1.3.6 Mexico Organoids Market, by Type
12. Pre & Post COVID-19 Impact
12.1 Pre & Post Covid-19 Impact
13. North America Organoids Market Industry Landscape
13.1 Overview
13.2 Growth Strategies Done by the Companies in the Market, (%)
13.3 Organic Developments
13.3.1 Overview
13.4 Inorganic Developments
13.4.1 Overview
14. North America Organoids Market, Key Company Profiles
14.1 STEMCELL Technologies Inc.
14.1.1 Key Facts
14.1.2 Business Description
14.1.3 Products and Services
14.1.4 Financial Overview
14.1.5 SWOT Analysis
14.1.6 Key Developments
14.2 Cellesce Ltd
14.2.1 Key Facts
14.2.2 Business Description
14.2.3 Products and Services
14.2.4 Financial Overview
14.2.5 SWOT Analysis
14.2.6 Key Developments
14.3 Organoid Therapeutics
14.3.1 Key Facts
14.3.2 Business Description
14.3.3 Products and Services
14.3.4 Financial Overview
14.3.5 SWOT Analysis
14.3.6 Key Developments
14.4.3Dnamics Inc.
14.4.1 Key Facts
14.4.2 Business Description
14.4.3 Products and Services
14.4.4 Financial Overview
14.4.5 SWOT Analysis
14.4.6 Key Developments
14.5 Thermo Fisher Scientific Inc
14.5.1 Key Facts
14.5.2 Business Description
14.5.3 Products and Services
14.5.4 Financial Overview
14.5.5 SWOT Analysis
14.5.6 Key Developments
14.6 Merck KGaA
14.6.1 Key Facts
14.6.2 Business Description
14.6.3 Products and Services
14.6.4 Financial Overview
14.6.5 SWOT Analysis
14.6.6 Key Developments
14.7 InSphero
14.7.1 Key Facts
14.7.2 Business Description
14.7.3 Products and Services
14.7.4 Financial Overview
14.7.5 SWOT Analysis
14.7.6 Key Developments
15. Appendix
15.1 About Us
15.2 Glossary of Terms

Table 1. North America Organoids Market Segmentation
Table 2. US Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Organ Type
Table 3. US Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Application
Table 4. US Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Source
Table 5. US Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Type
Table 6. Canada Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Organ Type
Table 7. Canada Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Application
Table 8. Canada Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Source
Table 9. Canada Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Type
Table 10. Mexico Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Organ Type
Table 11. Mexico Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Application
Table 12. Mexico Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Source
Table 13. Mexico Organoids Market Revenue and Forecast to 2030 (US$ Mn) – Type
Table 14. Organic Developments Done by Companies
Table 15. Inorganic Developments Done by Companies
Table 16. Glossary of Terms, North America Organoids Market

Figure 1. North America Organoids Market Segmentation, By Country
Figure 2. North America – PEST Analysis
Figure 3. North America Organoids Market – Key Industry Dynamics
Figure 4. Impact Analysis of Drivers and Restraints
Figure 5. North America Organoids Market Revenue (US$ Mn), 2022 – 2030
Figure 6. North America Organoids Market Revenue Share, by Organ Type 2022 & 2030 (%)
Figure 7. Stomach: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 8. Intestine: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 9. Liver: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 10. Pancreas: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 11. Lung: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 12. Brain: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 13. Kidney: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 14. Others: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 15. North America Organoids Market Revenue Share, by Application 2022 & 2030 (%)
Figure 16. Developmental Biology: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 17. Disease Pathology of Infectious Disease: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 18. Regenerative Medicine: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 19. Drug Toxicity and Efficacy Testing: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 20. Drug Discovery and Personalized Medicine: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 21. Others: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 22. North America Organoids Market Revenue Share, by Source 2022 & 2030 (%)
Figure 23. Pluripotent Stem Cells: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 24. Organ-specific Adult Stem Cells: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 25. North America Organoids Market Revenue Share, by Type 2022 & 2030 (%)
Figure 26. Instruments: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 27. Consumables: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 28. Services: North America Organoids Market – Revenue and Forecast to 2030 (US$ Million)
Figure 29. Organoids Market, 2022 (US$Mn)
Figure 30. North America Organoids Market, By Key Countries, 2022 And 2030 (%)
Figure 31. US Organoids Market Revenue and Forecast to 2030 (US$ Mn)
Figure 32. Canada Organoids Market Revenue and Forecast to 2030 (US$ Mn)
Figure 33. Mexico Organoids Market Revenue and Forecast to 2030 (US$ Mn)
Figure 34. Pre & Post Covid-19 Impact
Figure 35. Growth Strategies Done by the Companies in the Market, (%)