North America Microcarriers Market Forecast to 2030
North America Microcarriers Market Forecast to 2030 – Regional Analysis – by Product (Media & Reagents and Microcarrier Beads), Equipment (Bioreactors, Culture Vessels, and Others), Application (Biopharmaceutical Production, Cell and Gene Therapy, Tissue Engineering and Regenerative Medicine, and Others), and End User (Pharmaceutical and Biotechnology Companies, Contract Research Organizations & Contract Manufacturing Organizations, and Academic & Research Institutes)
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Description
Automation of Cell and Gene Therapy Manufacturing Services Fuels North America Microcarriers Market
Incorporating automation in cell and gene therapy manufacturing would lead to a reduced risk of contamination, improved consistency, and decreased cost of production. Lonza Cocoon and the CliniMACS Prodigy system from Miltenyi are a few of the devices available in the market that have been designed to enable the automation of most sequential unit operations for a CAR-T process within a single system. The rising demand for cell and gene therapies has shifted production from a small-volume process to a large-volume process worldwide. The progress of cell and gene therapy from an academic and clinical setting to mass production and commercialization further propels the demand for automation in commercial manufacturing. In July 2020, Thermo Fisher Scientific Inc. and Lyell Immunopharma partnered to develop processes to design effective cell therapies for cancer patients. Under this partnership, the companies aim to improve the capability of T-cells and support the development of an integrated current good manufacturing practice (cGMP) compliant platform (system and software), along with reagents, consumables, and instruments. Further, the US government-aided organizations are adopting automation in the manufacturing of cell therapies to increase the national production capabilities of the country. Thus, automation is emerging as a new trend in the microcarriers market.
North America Microcarriers Market Overview
The North America microcarriers market is segmented into the US, Canada, and Mexico. The US dominates the market in this region. The growth of the microcarriers market in North America is attributed to the increasing number of product launches by biotechnology and biopharmaceutical companies, the presence of key market players, and extensive R&D by various academic and research institutes. The rising prevalence of chronic diseases is a leading factor propelling the growth of the microcarrier market in the US. According to the Centers for Disease Control and Prevention (CDC), 6 in 10 Americans live with at least 1 chronic disease, such as heart disease and stroke, cancer, or diabetes. These diseases are the significant causes of mortality and disability in the US, and they also lead to significant costs of healthcare. There have been extensive clinical developments in the field of cell and gene therapies (CGT), owing to which the application range of these therapies has expanded in the past 5 years. With the approval of 12 new therapies and the commencement of over 2,900 clinical trials during the analysis period of 2016-2021, there have been extensive investments in CGT innovations. Technological advancements in gene editing, followed by clinical trials to evaluate the therapeutic effectiveness of the technique, are the other factors that have benefitted the microcarriers market in the US. For example, Poseida Therapeutics, Inc. received the US Food and Drug Administration (FDA) approval for its Investigational New Drug (IND) application for P-CD19CD20-ALLO1-the company’s first allogeneic dual CAR-T cell product candidate targeting both CD19 and CD20 antigens for the treatment of relapsed or refractory B-cell malignancies-being developed in partnership with Roche. In April 2023, Novel allogeneic CAR T-cell therapy delivered results in patients with metastatic clear cell renal cell carcinoma. Thus, increased participation and investments in clinical trials can accelerate the adoption and availability of new therapies. Researchers at the University of Texas MD Anderson Cancer Center led the Phase I trial and presented at the American Association for Cancer Research (AACR) Annual Meeting 2023. In August 2023, Astellas Pharma Inc. and Poseida Therapeutics, Inc. announced a strategic investment to support the advancement of Poseida’s commitment to redefining cancer cell therapy. Astellas invested US$ 50 million to license one of Poseida’s clinical-stage programs focusing on P-MUC1C-ALLO1, an allogeneic CAR T-cell therapy for multiple solid tumor indications. Thus, the demand for microcarriers is on the rise in the US with the increasing number of chronic disease cases and approval of different cell and gene therapies.
North America Microcarriers Market Revenue and Forecast to 2030 (US$ Million)
North America Microcarriers Market Segmentation
The North America microcarriers market is segmented into product, equipment, application, end user, and country.
Based on product, the North America microcarriers market is bifurcated into microcarriers beads and media & reagents. The microcarriers beads segment held a larger share of the North America microcarriers market in 2022.
In terms of equipment, the North America microcarriers market is segmented into bioreactors, culture vessels, and others. The bioreactors segment held the largest share of the North America microcarriers market in 2022.
Based on application, the North America microcarriers market is segmented into biopharmaceutical production, cell and gene therapy, tissue engineering and regenerative medicine, and other. The biopharmaceutical production segment held the largest share of the North America microcarriers market in 2022. Further, biopharmaceutical production segment is categorized into therapeutic protein production and vaccine production.
Based on end user, the North America microcarriers market is segmented into pharmaceutical & biotechnology companies, contract research organizations & contract manufacturing organizations, and academic & research institutes. The pharmaceutical & biotechnology companies segment held the largest share of the North America microcarriers market in 2022.
Based on country, the North America microcarriers market is segmented into the US, Canada, and Mexico. The US dominated the North America microcarriers market in 2022.
Teijin Ltd, Bio-Rad Laboratories Inc, Sartorius AG, Danaher Corp, Corning Inc, Eppendorf SE, Asahi Kasei Corp, and Polysciences Inc are some of the leading companies operating in the North America microcarriers market.
Summary Info
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According to the Research Team research, the North America microcarriers market was valued at US$ 736.67 million in 2022 and is expected to reach US$ 1,933.56 million by 2030, registering a CAGR of 12.8% from 2022 to 2030. Need for cell therapies with rising incidence of cancer and infectious diseases and increasing popularity of outsourcing cell and gene therapy manufacturing are among the critical factors attributed to the North America microcarriers market expansion.
World Health Organization (WHO) states that the global burden of cancer is estimated to rise to 27.5 million new cases and 16.3 million mortalities by 2040. The American Cancer Society projected 1,918,030 new cancer cases and 609,360 cancer deaths in the US for the year 2022, including nearly 350 deathsday from lung cancer, which is a major cause of cancer mortality. According to World Health Organization (WHO) tuberculosis (TB) is the 13th top cause of death globally and the second leading infectious disease after COVID-19. According to the WHO, there were 1.5 million deaths caused by TB in 2020 (including 214,000 people affected by HIV). In 2020, WHO projected that 10 million people had TB globally, including 1.1 million children, 3.3 million women, and 5.6 million men. TB is present in all age groups and countries. Furthermore, infectious diseases are caused by infectious agents, such as viruses, bacteria, parasites, fungi, and toxic products. HIV is a major public health issue across the world. According to The Joint United Nations Programme on HIVAIDS (UNAIDS), ~ 37.7 million people had HIV in 2020 globally. Out of these, 1.7 million were children aged 0-14 years, and 36 million were adults. Also, more than half (53%) were girls and women. 1.5 million new HIV cases were reported in 2020 globally. Similarly, hepatitis is inflammation of the liver caused by a viral infection. The five main strains of hepatitis viruses are A, B, C, D, and E. According to World Health Organization (WHO), around 58 million people across the globe have chronic hepatitis C virus infection, and ~1.5 million new infections occur every year. The increasing incidence of diseases where cell therapy can be effectively applied, such as cancers, urinary problems, autoimmune diseases, and infectious diseases, is associated with the growth of the microcarriers market. Microcarriers are tiny spheres or particles (typically 90-300 µm in diameter) used for culturing adherent cells in stirred-tank bioreactors. With the growing incidence of cancer and various infectious diseases, the need for proper medication and vaccines arises, which favors the microcarriers market growth.
On the contrary, high cost of biologics and cell-based therapies hampers the North America microcarriers market.
Based on product, the North America microcarriers market is bifurcated into microcarriers beads and media & reagents. The microcarriers beads segment held 69.6% share of North America microcarriers market in 2022, amassing US$ 513.02 million. It is projected to garner US$ 1,369.85 million by 2030 to expand at 13.1% CAGR during 2022-2030.
In terms of equipment, the North America microcarriers market is categorized into bioreactors, culture vessels, and others. The bioreactors segment held 64.6% share of North America microcarriers market in 2022, amassing US$ 476.17 million. It is projected to garner US$ 1,274.40 million by 2030 to expand at 13.1% CAGR during 2022-2030.
Based on application, the North America microcarriers market is segmented into biopharmaceutical production, cell and gene therapy, tissue engineering and regenerative medicine, and other. The biopharmaceutical production beads segment held 50.7% share of North America microcarriers market in 2022, amassing US$ 373.42 million. It is projected to garner US$ 1,018.83 million by 2030 to expand at 13.4% CAGR during 2022-2030. Further, biopharmaceutical production segment is categorized into therapeutic protein production and vaccine production.
Based on end user, the North America microcarriers market is segmented into pharmaceutical & biotechnology companies, contract research organizations & contract manufacturing organizations, and academic & research institutes. The pharmaceutical & biotechnology companies segment held 55.1% share of North America microcarriers market in 2022, amassing US$ 405.83 million. It is projected to garner US$ 1,091.36 million by 2030 to expand at 13.2% CAGR during 2022-2030.
By country, the North America microcarriers market has been categorized into the US, Canada, and Mexico. Our regional analysis states that the US captured 83.1% share of North America microcarriers market in 2022. It was assessed at US$ 612.22 million in 2022 and is likely to hit US$ 1,633.04 million by 2030, exhibiting a CAGR of 13.0% during 2022-2030.
Key players operating in the North America microcarriers market are Teijin Ltd, Bio-Rad Laboratories Inc, Sartorius AG, Danaher Corp, Corning Inc, Eppendorf SE, Asahi Kasei Corp, and Polysciences Inc, among others.
In June 2023, Teijin Ltd introduced the new nonwoven microcarriers for speedy and large-scale cell culture. This scaffolding substance promotes three-dimensional adhesion and growth for a variety of cell types.
In May 2022, Saint-Gobain Life Sciences released beadMATRIX for mesenchymal stromal cells (MSCs). beadMATRIX are ready-to-use, pre-coated microcarriers free of animal components that are used to cultivate superior MSCs in vitro. Shaker bags, stirred tanks, vertical wheel bioreactors, and shaker flasks are the perfect environments for beadMATRIX
o Highlights key business priorities in order to assist companies to realign their business strategies.
o The key findings and recommendations highlight crucial progressive industry trends in North America microcarriers market, thereby allowing players across the value chain to develop effective long-term strategies.
o Develop modify business expansion plans by using substantial growth offering developed and emerging markets.
o Scrutinize in-depth North America market trends and outlook coupled with the factors driving the market, as well as those hindering it.
o Enhance the decision-making process by understanding the strategies that underpin security interest with respect to client products, segmentation, pricing, and distribution.
TABLE OF CONTENTS
1. Introduction
1.1 the Research Team Research Report Guidance
1.2 Market Segmentation
2. Executive Summary
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. North America Microcarriers Market – Key Industry Dynamics
4.1 Key Market Drivers:
4.1.1 Need for Cell Therapies with Rising Incidence of Cancer and Infectious Diseases
4.1.2 Increasing Popularity of Outsourcing Cell and Gene Therapy Manufacturing
4.1.3 Surge in Adoption of Regenerative Medicine
4.2 Market Restraints
4.2.1 High Cost of Biologics and Cell-based Therapies
4.3 Market Opportunities
4.3.1 Strategic Initiatives and Innovative Products by Microcarrier Manufacturers
4.4 Future Trends
4.4.1 Automation of Cell and Gene Therapy Manufacturing Services
4.5 Impact Analysis
5. Microcarriers Market – North America Market Analysis
5.1 Microcarriers Market Revenue (US$ Mn), 2022 – 2030
6. North America Microcarriers Market – Revenue and Forecast to 2030 – by Product
6.1 Overview
6.2 Microcarriers Market Revenue Share, by Product 2022 & 2030 (%)
6.3 Microcarrier Beads
6.3.1 Overview
6.3.2 Microcarrier Beads: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
6.4 Media and Reagents
6.4.1 Overview
6.4.2 Media and Reagents: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
7. North America Microcarriers Market – Revenue and Forecast to 2030 – by Equipment
7.1 Overview
7.2 Microcarriers Market Revenue Share, by Equipment 2022 & 2030 (%)
7.3 Bioreactors
7.3.1 Overview
7.3.2 Bioreactors: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
7.4 Culture Vessels
7.4.1 Overview
7.4.2 Culture Vessels: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
7.5 Others
7.5.1 Overview
7.5.2 Others: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
8. North America Microcarriers Market – Revenue and Forecast to 2030 – by Application
8.1 Overview
8.2 Microcarriers Market Revenue Share, by Application 2022 & 2030 (%)
8.3 Biopharmaceutical Production
8.3.1 Overview
8.3.2 Biopharmaceutical Production: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
8.3.3 Therapeutic Protein Production: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
8.3.4 Vaccine Production: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
8.4 Cell and Gene Therapy
8.4.1 Overview
8.4.2 Cell and Gene Therapy: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
8.5 Tissue Engineering and Regenerative Medicine
8.5.1 Overview
8.5.2 Tissue Engineering and Regenerative Medicine: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
8.6 Others
8.6.1 Overview
8.6.2 Others: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
9. North America Microcarriers Market Revenue and Forecasts To 2030 – End User
9.1 Overview
9.2 North America Microcarriers Market Share by End User – 2022 & 2030 (%)
9.3 Pharmaceutical and Biotechnology Companies
9.3.1 Overview
9.3.2 Pharmaceutical and Biotechnology Companies: Microcarriers Market- Revenue and Forecast to 2030 (US$ Million)
9.4 Contract Research Organizations and Contract Manufacturing Organizations
9.4.1 Overview
9.4.2 Contract Research Organizations and Contract Manufacturing Organizations: Microcarriers Market- Revenue and Forecast to 2028 (US$ Million)
9.5 Academic and Research Institutes
9.5.1 Overview
9.5.2 Academic and Research Institutes: Microcarriers Market- Revenue and Forecast to 2028 (US$ Million)
10. North America Microcarriers Market Revenue and Forecasts to 2030 – Country Analysis
10.1 North America Microcarriers Market, Revenue and Forecast To 2030
10.1.1 Overview
10.1.2 North America: Microcarriers Market, by Country
10.1.2.1 US
10.1.2.1.1 Overview
10.1.2.1.2 US: Microcarriers Market Revenue and Forecast to 2030 (US$ Mn)
10.1.2.1.3 US: Microcarriers Market, by Product
10.1.2.1.4 US: Microcarriers Market, by Equipment
10.1.2.1.5 US: Microcarriers Market, by Application
10.1.2.1.5.1 US: Microcarriers Market, by Biopharmaceutical Production
10.1.2.1.6 US: Microcarriers Market, by End User
10.1.2.2 Canada
10.1.2.2.1 Overview
10.1.2.2.2 Canada: Microcarriers Market Revenue and Forecast to 2030 (US$ Mn)
10.1.2.2.3 Canada: Microcarriers Market, by Product
10.1.2.2.4 Canada: Microcarriers Market, by Equipment
10.1.2.2.5 Canada: Microcarriers Market, by Application
10.1.2.2.5.1 Canada: Microcarriers Market, by Biopharmaceutical Production
10.1.2.2.6 Canada: Microcarriers Market, by End User
10.1.2.3 Mexico
10.1.2.3.1 Overview
10.1.2.3.2 Mexico: Microcarriers Market Revenue and Forecast to 2030 (US$ Mn)
10.1.2.3.3 Mexico: Microcarriers Market, by Product
10.1.2.3.4 Mexico: Microcarriers Market, by Equipment
10.1.2.3.5 Mexico: Microcarriers Market, by Application
10.1.2.3.5.1 Mexico: Microcarriers Market, by Biopharmaceutical Production
10.1.2.3.6 Mexico: Microcarriers Market, by End User
11. Microcarriers Market-Industry Landscape
11.1 Overview
11.2 Organic Growth Strategies
11.2.1 Overview
11.3 Inorganic Growth Strategies
11.3.1 Overview
12. Company Profiles
12.1 Teijin Ltd
12.1.1 Key Facts
12.1.2 Business Description
12.1.3 Products and Services
12.1.4 Financial Overview
12.1.5 SWOT Analysis
12.1.6 Key Developments
12.2 Bio-Rad Laboratories Inc
12.2.1 Key Facts
12.2.2 Business Description
12.2.3 Products and Services
12.2.4 Financial Overview
12.2.5 SWOT Analysis
12.2.6 Key Developments
12.3 Sartorius AG
12.3.1 Key Facts
12.3.2 Business Description
12.3.3 Products and Services
12.3.4 Financial Overview
12.3.5 SWOT Analysis
12.3.6 Key Developments
12.4 Danaher Corp
12.4.1 Key Facts
12.4.2 Business Description
12.4.3 Products and Services
12.4.4 Financial Overview
12.4.5 SWOT Analysis
12.4.6 Key Developments
12.5 Corning Inc
12.5.1 Key Facts
12.5.2 Business Description
12.5.3 Products and Services
12.5.4 Financial Overview
12.5.5 SWOT Analysis
12.5.6 Key Developments
12.6 Eppendorf SE
12.6.1 Key Facts
12.6.2 Business Description
12.6.3 Products and Services
12.6.4 Financial Overview
12.6.5 SWOT Analysis
12.6.6 Key Developments
12.7 Asahi Kasei Corp
12.7.1 Key Facts
12.7.2 Business Description
12.7.3 Products and Services
12.7.4 Financial Overview
12.7.5 SWOT Analysis
12.7.6 Key Developments
12.8 Polysciences Inc
12.8.1 Key Facts
12.8.2 Business Description
12.8.3 Products and Services
12.8.4 Financial Overview
12.8.5 SWOT Analysis
12.8.6 Key Developments
13. Appendix
13.1 About the Research Team
13.2 Glossary of Terms
LIST OF TABLES
Table 1. Microcarriers Market Segmentation
Table 2. US Microcarriers Market, by Product – Revenue and Forecast to 2030 (USD Million)
Table 3. US Microcarriers Market, by Equipment – Revenue and Forecast to 2030 (USD Million)
Table 4. US Microcarriers Market, by Application – Revenue and Forecast to 2030 (USD Million)
Table 5. US Microcarriers Market, by Biopharmaceutical Production – Revenue and Forecast to 2030 (USD Million)
Table 6. US: Microcarriers Market Revenue and Forecast To 2030 (US$ Mn) – End User
Table 7. Canada Microcarriers Market, by Product – Revenue and Forecast to 2030 (USD Million)
Table 8. Canada Microcarriers Market, by Equipment – Revenue and Forecast to 2030 (USD Million)
Table 9. Canada Microcarriers Market, by Application – Revenue and Forecast to 2030 (USD Million)
Table 10. Canada Microcarriers Market, by Biopharmaceutical Production – Revenue and Forecast to 2030 (USD Million)
Table 11. Canada: Microcarriers Market Revenue and Forecast To 2030 (US$ Mn) – End User
Table 12. Mexico Microcarriers Market, by Product – Revenue and Forecast to 2030 (USD Million)
Table 13. Mexico Microcarriers Market, by Equipment – Revenue and Forecast to 2030 (USD Million)
Table 14. Mexico Microcarriers Market, by Application – Revenue and Forecast to 2030 (USD Million)
Table 15. Mexico Microcarriers Market, by Biopharmaceutical Production – Revenue and Forecast to 2030 (USD Million)
Table 16. Mexico: Microcarriers Market Revenue and Forecast To 2030 (US$ Mn) – End User
Table 17. Recent Organic Growth Strategies in Microcarriers Market
Table 18. Recent Inorganic Growth Strategies in the Microcarriers Market
Table 19. Glossary of Terms
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LIST OF FIGURES
Figure 1. Microcarriers Market Segmentation, By Country
Figure 2. Key Insights
Figure 3. Microcarriers Market – Key Industry Dynamics
Figure 4. Impact Analysis of Drivers and Restraints for Microcarriers Market
Figure 5. Microcarriers Market Revenue (US$ Mn), 2022 – 2030
Figure 6. Microcarriers Market Revenue Share, by Product 2022 & 2030 (%)
Figure 7. Microcarrier Beads: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 8. Media and Reagents: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 9. Microcarriers Market Revenue Share, by Equipment 2022 & 2030 (%)
Figure 10. Bioreactors: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 11. Culture Vessels: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 12. Others: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 13. Microcarriers Market Revenue Share, by Application 2022 & 2030 (%)
Figure 14. Biopharmaceutical Production: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 15. Therapeutic Protein Production: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 16. Vaccine Production: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 17. Cell and Gene Therapy: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 18. Tissue Engineering and Regenerative Medicine: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 19. Others: Microcarriers Market – Revenue and Forecast to 2030 (US$ Million)
Figure 20. North America Microcarriers Market Share by End User – 2022 & 2030 (%)
Figure 21. Pharmaceutical and Biotechnology Companies: Microcarriers Market Revenue and Forecasts To 2030 (US$ Million)
Figure 22. Contract Research Organizations and Contract Manufacturing Organizations: Microcarriers Market Revenue and Forecasts To 2030 (US$ Million)
Figure 23. Academic and Research Institutes: Microcarriers Market Revenue and Forecasts To 2030 (US$ Million)
Figure 24. Microcarriers Market, 2022 (US$Mn)
Figure 25. North America: Microcarriers Market, By Countries, 2022 And 2030 (%)
Figure 26. US: Microcarriers Market Revenue and Forecast to 2030 (US$ Mn)
Figure 27. Canada: Microcarriers Market Revenue and Forecast to 2030 (US$ Mn)
Figure 28. Mexico: Microcarriers Market Revenue and Forecast to 2030 (US$ Mn)
The List of Companies – North America Microcarriers Market
1. Teijin Ltd
2. Bio-Rad Laboratories Inc
3. Sartorius AG
4. Danaher Corp
5. Corning Inc
6. Eppendorf SE
7. Asahi Kasei Corp
8. Polysciences Inc
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