Europe Upstream Bioprocessing Market Forecast to 2030

At 13.4% CAGR, Europe Upstream Bioprocessing Market is Speculated to be Worth US$ 7,069.78 Million by 2030, says the Research Team.

According to the Research Team’ research, the Europe upstream bioprocessing market was valued at US$ 2,581.59 million in 2022 and is expected to reach US$ 7,069.78 million by 2030, registering a CAGR of 13.4% from 2022 to 2030. Technological advancements and Rapid growth of pharmaceutical and biotechnology industries are among the critical factors attributed to the Europe upstream bioprocessing market expansion.

The upstream bioprocessing market is experiencing a wave of technological advancements, presenting considerable industry opportunities. These advancements include innovative developments in cell culture systems, bioreactor design, process monitoring, and control, as well as the integration of automation and digitalization. In September 2023, Repligen Corporation and Sartorius introduced an integrated bioreactor system. Repligen’s XCell Alternating Tangential Flow (ATF) upstream intensification technology has been integrated into the Sartorius Biostat stirred-tank reactor (STR). This bioreactor technology is designed to make the application of N perfusion and intensified seed train easier for biopharmaceutical firms. An embedded XCell ATF hardware and software module that combines integrated process analytical technologies with predefined advanced control recipes is incorporated into Biostat STR. This module is intended to simplify the management of cell growth and enhance cell retention in perfusion procedures, eliminating the need for a separate cell retention control tower. Such modern products feature enhanced process efficiency, scalability, and adaptability, which are crucial for meeting the evolving demands of biopharmaceutical production.

Advanced cell culture media formulations and next-generation bioreactor technologies are contributing to the optimization of upstream bioprocessing, in turn, enabling higher product yields, improved product quality, and the efficient production of complex biologics. The ongoing integration of advanced analytics and real-time process monitoring is revolutionizing data-driven decision-making in bioprocessing, driving precision and process optimization opportunities. Progress in biotechnology also fosters the development of flexible and modular manufacturing platforms. Additionally, the convergence of machine learning, artificial intelligence, and predictive analytics is paving the way for predictive bioprocessing, thereby unlocking proactive process control, quality assurance, and cost optimization opportunities. Thus, technological advancements in upstream bioprocessing are reshaping the industry, presenting new avenues for innovation, efficiency, and adaptability.

On the contrary, stringent regulatory framework hampers the growth of Europe upstream bioprocessing market.

Based on product type, the Europe upstream bioprocessing market is segmented into bioreactors/fermenters, cell culture, filters, bags and containers, and others. The bioreactors/fermenters segment held 35.0% market share in 2022, amassing US$ 902.31 million. It is projected to garner US$ 2,444.28 million by 2030 to expand at 13.3% CAGR during 2022-2030.

Based on workflow, the Europe upstream bioprocessing market is segmented into media preparation, cell culture, and cell separation. The cell separation segment held 41.2% share of Europe upstream bioprocessing market in 2022, amassing US$ 1,063.62 million. It is projected to garner US$ 3,016.31 million by 2030 to expand at 13.9% CAGR during 2022-2030.

By usage type, the Europe upstream bioprocessing market is bifurcated into single-use and multi-use. The single-use segment held 55.1% share of Europe upstream bioprocessing market in 2022, amassing US$ 1,421.76 million. It is projected to garner US$ 3,982.50 million by 2030 to expand at 13.7% CAGR during 2022-2030.

In terms of mode, the Europe upstream bioprocessing market is bifurcated into In-house and outsourced. The In-house segment held 53.9% share of Europe upstream bioprocessing market in 2022, amassing US$ 1,390.44 million. It is projected to garner US$ 3,718.94 million by 2030 to expand at 13.1% CAGR during 2022-2030.

Based on country, the Europe upstream bioprocessing market has been categorized into the UK, Germany, France, Italy, Spain, and the Rest of Europe. Our regional analysis states that Germany captured 25.4% share of Europe upstream bioprocessing market in 2022. It was assessed at US$ 655.72 million in 2022 and is likely to hit US$ 1,847.73 million by 2030, exhibiting a CAGR of 13.8% during 2022-2030.

Key players operating in the Europe upstream bioprocessing market are Thermo Fisher Scientific Inc, Esco Micro Pte Ltd, Cellexus International Ltd, Sartorius AG, Getinge AB, Merck KGaA, Corning Inc, and Entegris Inc, among others.

In December 2023, Merck has acquired Erbi Biosystems, a Massachusetts-based company that developed the “Breez” 2 ml micro-bioreactor platform technology. Merck’s upstream therapeutic protein portfolio is boosted by the purchase, enabling it to promptly develop lab-scale protocols for scalable cell-based perfusion bioreactor processes with capacities ranging from 2 ml to 2000 l. Additionally, it offers opportunities for further study and advancement in cutting-edge modality applications, like cell therapies.

In October 2023, Getinge AB acquired High Purity New England, Inc for US$ 120 million. By the end of 2024, the company will fully integrate High Purity New England, Inc. The acquisition has helped Getinge AB acquire a comprehensive range of proprietary and distributed products from drug discovery, upstream and downstream processing, and fill-and-finish.

o Save and reduce time carrying out entry-level research by identifying the growth, size, leading players, and segments in the Europe upstream bioprocessing market.
o Highlights key business priorities in order to assist companies to realign their business strategies.
o The key findings and recommendations highlight crucial progressive industry trends in Europe upstream bioprocessing market, thereby allowing players across the value chain to develop effective long-term strategies.
o Develop/modify business expansion plans by using substantial growth offering developed and emerging markets.
o Scrutinize in-depth Europe market trends and outlook coupled with the factors driving the market, as well as those hindering it.
o Enhance the decision-making process by understanding the strategies that underpin security interest with respect to client products, segmentation, pricing, and distribution.

TABLE OF CONTENTS

1. Introduction
1.1 The the Reporting Teams Research Report Guidance
1.2 Market Segmentation
2. Executive Summary
2.1 Key Insights
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. Europe Upstream Bioprocessing Market Landscape
4.1 Overview
4.2 PEST Analysis
5. Europe Upstream Bioprocessing Market – Key Market Dynamics
5.1 Market Drivers
5.1.1 Commercial Use of Single-Use Bioreactors
5.1.2 Outsourcing of Biopharmaceutical Manufacturing
5.1.3 Rapid Growth of Pharmaceutical and Biotechnology Industries
5.2 Market Restraints
5.2.1 Stringent Regulatory Framework
5.3 Market Opportunities
5.3.1 Technological Advancements
5.4 Future Trends
5.4.1 Increasing Investments in R&D in Biopharmaceutical Industry
5.5 Impact of Drivers and Restraints:
6. Upstream Bioprocessing Market – Europe Analysis
7. Europe Upstream Bioprocessing Market Analysis – by Product Type
7.1 Bioreactors/Fermenters
7.1.1 Overview
7.1.2 Bioreactors/Fermenters: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
7.2 Cell Culture
7.2.1 Overview
7.2.2 Cell Culture: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
7.3 Filters
7.3.1 Overview
7.3.2 Filters: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
7.4 Bags and Containers
7.4.1 Overview
7.4.2 Bags and Containers: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
7.5 Others
7.5.1 Overview
7.5.2 Others: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
8. Europe Upstream Bioprocessing Market Analysis – by Workflow
8.1 Media Preparation
8.1.1 Overview
8.1.2 Media Preparation: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
8.2 Cell Culture
8.2.1 Overview
8.2.2 Cell Culture: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
8.3 Cell Separation
8.3.1 Overview
8.3.2 Cell Separation: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
9. Europe Upstream Bioprocessing Market Analysis – by Usage Type
9.1 Single-use
9.1.1 Overview
9.1.2 Single-use: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
9.2 Multi-use
9.2.1 Overview
9.2.2 Multi-use: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
10. Europe Upstream Bioprocessing Market Analysis – by Mode
10.1 In-house
10.1.1 Overview
10.1.2 In-house: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
10.2 Outsourced
10.2.1 Overview
10.2.2 Outsourced: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11. Europe Upstream Bioprocessing Market – Country Analysis
11.1 Europe Market Overview
11.1.1 Europe: Upstream Bioprocessing Market – Revenue and Forecast Analysis – by Country
11.1.1.1 Europe: Upstream Bioprocessing Market – Revenue and Forecast Analysis – by Country
11.1.1.2 UK
11.1.1.3 UK: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11.1.1.3.1 UK: Upstream Bioprocessing Market Breakdown, by Product Type
11.1.1.3.2 UK: Upstream Bioprocessing Market Breakdown, by Workflow
11.1.1.3.3 UK: Upstream Bioprocessing Market Breakdown, by Usage Type
11.1.1.3.4 UK: Upstream Bioprocessing Market Breakdown, by Mode
11.1.1.4 Germany
11.1.1.5 Germany: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11.1.1.5.1 Germany: Upstream Bioprocessing Market Breakdown, by Product Type
11.1.1.5.2 Germany: Upstream Bioprocessing Market Breakdown, by Workflow
11.1.1.5.3 Germany: Upstream Bioprocessing Market Breakdown, by Usage Type
11.1.1.5.4 Germany: Upstream Bioprocessing Market Breakdown, by Mode
11.1.1.6 France
11.1.1.7 France: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11.1.1.7.1 France: Upstream Bioprocessing Market Breakdown, by Product Type
11.1.1.7.2 France: Upstream Bioprocessing Market Breakdown, by Workflow
11.1.1.7.3 France: Upstream Bioprocessing Market Breakdown, by Usage Type
11.1.1.7.4 France: Upstream Bioprocessing Market Breakdown, by Mode
11.1.1.8 Italy
11.1.1.9 Italy: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11.1.1.9.1 Italy: Upstream Bioprocessing Market Breakdown, by Product Type
11.1.1.9.2 Italy: Upstream Bioprocessing Market Breakdown, by Workflow
11.1.1.9.3 Italy: Upstream Bioprocessing Market Breakdown, by Usage Type
11.1.1.9.4 Italy: Upstream Bioprocessing Market Breakdown, by Mode
11.1.1.10 Spain
11.1.1.11 Spain: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11.1.1.11.1 Spain: Upstream Bioprocessing Market Breakdown, by Product Type
11.1.1.11.2 Spain: Upstream Bioprocessing Market Breakdown, by Workflow
11.1.1.11.3 Spain: Upstream Bioprocessing Market Breakdown, by Usage Type
11.1.1.11.4 Spain: Upstream Bioprocessing Market Breakdown, by Mode
11.1.1.12 Rest of Europe
11.1.1.13 Rest of Europe: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
11.1.1.13.1 Rest of Europe: Upstream Bioprocessing Market Breakdown, by Product Type
11.1.1.13.2 Rest of Europe: Upstream Bioprocessing Market Breakdown, by Workflow
11.1.1.13.3 Rest of Europe: Upstream Bioprocessing Market Breakdown, by Usage Type
11.1.1.13.4 Rest of Europe: Upstream Bioprocessing Market Breakdown, by Mode
12. Industry Landscape
12.1 Overview
12.2 Growth Strategies in Upstream Bioprocessing Market
12.3 Organic Growth Strategies
12.3.1 Overview
12.4 Inorganic Growth Strategies
12.4.1 Overview
13. Company Profiles
13.1 Thermo Fisher Scientific Inc
13.1.1 Key Facts
13.1.2 Business Description
13.1.3 Products and Services
13.1.4 Financial Overview
13.1.5 SWOT Analysis
13.1.6 Key Developments
13.2 Esco Micro Pte Ltd
13.2.1 Key Facts
13.2.2 Business Description
13.2.3 Products and Services
13.2.4 Financial Overview
13.2.5 SWOT Analysis
13.2.6 Key Developments
13.3 Cellexus International Ltd
13.3.1 Key Facts
13.3.2 Business Description
13.3.3 Products and Services
13.3.4 Financial Overview
13.3.5 SWOT Analysis
13.3.6 Key Developments
13.4 Sartorius AG
13.4.1 Key Facts
13.4.2 Business Description
13.4.3 Products and Services
13.4.4 Financial Overview
13.4.5 SWOT Analysis
13.4.6 Key Developments
13.5 Getinge AB
13.5.1 Key Facts
13.5.2 Business Description
13.5.3 Products and Services
13.5.4 Financial Overview
13.5.5 SWOT Analysis
13.5.6 Key Developments
13.6 Merck KGaA
13.6.1 Key Facts
13.6.2 Business Description
13.6.3 Products and Services
13.6.4 Financial Overview
13.6.5 SWOT Analysis
13.6.6 Key Developments
13.7 Corning Inc
13.7.1 Key Facts
13.7.2 Business Description
13.7.3 Products and Services
13.7.4 Financial Overview
13.7.5 SWOT Analysis
13.7.6 Key Developments
13.8 Entegris Inc
13.8.1 Key Facts
13.8.2 Business Description
13.8.3 Products and Services
13.8.4 Financial Overview
13.8.5 SWOT Analysis
13.8.6 Key Developments
14. Appendix
14.1 About The the Reporting Teams
14.2 Glossary of Terms

LIST OF TABLES

Table 1. Upstream Bioprocessing Market Segmentation
Table 2. Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 3. Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 4. Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 5. Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 6. Europe: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Country
Table 7. UK: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 8. UK: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 9. UK: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 10. UK: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 11. Germany: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 12. Germany: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 13. Germany: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 14. Germany: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 15. France: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 16. France: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 17. France: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 18. France: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 19. Italy: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 20. Italy: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 21. Italy: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 22. Italy: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 23. Spain: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 24. Spain: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 25. Spain: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 26. Spain: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 27. Rest of Europe: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Product Type
Table 28. Rest of Europe: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Workflow
Table 29. Rest of Europe: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Usage Type
Table 30. Rest of Europe: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million) – by Mode
Table 31. Recent Organic Growth Strategies in Upstream Bioprocessing Market
Table 32. Recent Inorganic Growth Strategies in the Upstream Bioprocessing Market
Table 33. Glossary of Terms, Upstream Bioprocessing Market

LIST OF FIGURES

Figure 1. Upstream Bioprocessing Market Segmentation, by Country
Figure 2. PEST Analysis
Figure 3. Europe Upstream Bioprocessing Market – Key Market Dynamics
Figure 4. Impact Analysis of Drivers and Restraints
Figure 5. Upstream Bioprocessing Market Revenue (US$ Million), 2020-2030
Figure 6. Upstream Bioprocessing Market Share (%) – by Product Type (2022 and 2030)
Figure 7. Bioreactors/Fermenters: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 8. Cell Culture: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 9. Filters: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 10. Bags and Containers: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 11. Others: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 12. Upstream Bioprocessing Market Share (%) – by Workflow (2022 and 2030)
Figure 13. Media Preparation: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 14. Cell Culture: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 15. Cell Separation: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 16. Upstream Bioprocessing Market Share (%) – by Usage Type (2022 and 2030)
Figure 17. Single-use: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 18. Multi-use: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 19. Upstream Bioprocessing Market Share (%) – by Mode (2022 and 2030)
Figure 20. In-house: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 21. Outsourced: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 22. Europe: Upstream Bioprocessing Market, by Key Country – Revenue (2022) (US$ Million)
Figure 23. Europe: Upstream Bioprocessing Market Breakdown, by Key Countries, 2022 and 2030 (%)
Figure 24. UK: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 25. Germany: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 26. France: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 27. Italy: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 28. Spain: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 29. Rest of Europe: Upstream Bioprocessing Market – Revenue and Forecast to 2030 (US$ Million)
Figure 30. Growth Strategies in Upstream Bioprocessing Market