Europe Endothelial Dysfunction Market Forecast to 2028

According to the research team’ research,, the Europe endothelial dysfunction market was valued at US$ 611.28 million in 2022 and is expected to reach US$ 776.37 million by 2028, registering a CAGR of 4.1% from 2022 to 2028. Increasing incidences of cardiovascular diseases and rising incidences of high cholesterol, diabetes and obesity are the critical factors attributed to the Europe endothelial dysfunction market expansion.

Examining endothelial function can improve risk stratification, improve early disease detection, and assess vascular response to therapeutic interventions. There are studies to understand the pathophysiological mechanisms underlying endothelial dysfunction and atherosclerosis progression in a better way and identify new biomarkers and therapeutic strategies to prevent endothelial dysfunction and atherosclerosis to reduce the risk of developing coronary artery disease (CAD) and related complications. Using liquid biopsies and new molecular biology techniques has enabled the identification of a growing list of molecular and cellular markers of endothelial dysfunction that have provided insight into the molecular basis of atherosclerosis as well as potential biomarkers and therapeutic targets for the prevention and treatment of atherosclerosis and CAD.

Research on biomarkers and their clinical application has increased exponentially over the last few decades. Invaluable insight into the pathophysiology of atherosclerosis and the development of novel therapies have been provided by systemic biomarkers. Endothelial dysfunction and inflammation play a central role in the development and progression of CAD. Inflammatory mediators are secreted by inflammatory and vascular cells in atherosclerotic plaque or by organs such as the liver or adipose tissue. Therefore, several inflammation-related factors are considered biomarkers for the early prediction of coronary artery disease. Clinical studies have extensively examined acute phase proteins, cytokines, adhesion molecules, and microparticles as endothelial dysfunction and inflammation markers.

On the contrary, disadvantages associated with the techniques for screening of endothelial dysfunction hurdles the growth of Europe endothelial dysfunction market.

Based on cause, the Europe endothelial dysfunction market is segmented into hypertension, hypercholestrolaemia, obesity, diabetes, behcet’s disease, and others. The hypertension segment held 32.8% share of Europe endothelial dysfunction market in 2022, amassing US$ 200.71 million. It is projected to garner US$ 262.23 million by 2028 to expand at 4.6% CAGR during 2022–2028.

Based on test type, the Europe endothelial dysfunction market is segmented into invasive test and non-invasive test. The invasive test segment held 73.9% share of Europe endothelial dysfunction market in 2022, amassing US$ 451.80 million. It is projected to garner US$ 565.80 million by 2028 to expand at 3.8% CAGR during 2022–2028. The non-invasive test segment is further subsegmented into flow mediated dilatory, peripheral arterial tonometry (PAT), venous occlusion pletismography, circulating markers, and others.

Based on end user, the Europe endothelial dysfunction market has been categorized into hospitals, diagnostic centers, clinics, and others. The hospitals segment held 52.1% share of Europe endothelial dysfunction market in 2022, amassing US$ 318.43 million. It is projected to garner US$ 412.44 million by 2028 to expand at 4.4% CAGR during 2022–2028.

Based on country, the Europe endothelial dysfunction market has been categorized into the UK, Germany, Italy, France, Spain, and the Rest of Europe. Our regional analysis states that Germany captured 29.2% share of Europe endothelial dysfunction market in 2022. It was assessed at US$ 178.57 million in 2022 and is likely to hit US$ 237.54 million by 2028, exhibiting a CAGR of 4.9% during 2022–2028.

Key players operating in the Europe endothelial dysfunction are ZOLL Medical Corp, Sphingo Tec GmbH, The Polymath Co, SMART Medical Ltd, Alam Medical SaRl, and Medizinische Messtechnik GmbH, among others.

In July 2020, SphingoTec launched point-of-care test for bio-ADM, a biomarker for life threatening endothelial dysfunction. The company launched its IB10 sphingotest bio-ADM, a CE-IVD-marked point-of-care test to quantitatively determine blood levels of Bioactive Adrenomedullin (bio-ADM).

1. Introduction
1.1 Scope of the Study
1.2 The Research Team Report Guidance
1.3 Market Segmentation
1.3.1 Europe Endothelial Dysfunction Market – by Cause
1.3.2 Europe Endothelial Dysfunction Market – by Test Type
1.3.3 Europe Endothelial Dysfunction Market – by End User
1.3.4 Europe Endothelial Dysfunction Market – by Country
2. Europe Endothelial Dysfunction Market – Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. Europe Endothelial Dysfunction Market – Market Landscape
4.1 Overview
4.2 PEST Analysis
4.2.1 Europe PEST Analysis
4.3 Expert Opinion
5. Europe Endothelial Dysfunction Market – Key Market Dynamics
5.1 Market Drivers
5.1.1 Increasing Incidences of Cardiovascular Diseases
5.1.2 Rising Incidences of High Cholesterol, Diabetes And Obesity
5.2 Market Restraints
5.2.1 Disadvantages Associated with the Techniques for Screening of Endothelial Dysfunction
5.3 Market Opportunities
5.3.1 Rising Usage of Novel Biomarkers and Therapeutic Strategies
5.4 Future Trends
5.4.1 Use of Noninvasive Methods to Assess Endothelial Dysfunction
5.5 Impact Analysis
6. Endothelial Dysfunction Market – Europe Analysis
6.1 Europe Endothelial Dysfunction Market Revenue Forecast and Analysis
7. Europe Endothelial Dysfunction Market Analysis – by Cause
7.1 Overview
7.2 Europe Endothelial Dysfunction Market, By Cause, 2022 & 2028 (%)
7.3 Hypertension
7.3.1 Overview
7.3.2 Hypertension: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
7.4 Diabetes
7.4.1 Overview
7.4.2 Diabetes: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
7.5 Hypercholestrolaemia
7.5.1 Overview
7.5.2 Hypercholestrolaemia: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
7.6 Behcet’s Disease
7.6.1 Overview
7.6.2 Behcet’s Disease: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
7.7 Obesity
7.7.1 Overview
7.7.2 Obesity: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
7.8 Others
7.8.1 Overview
7.8.2 Others: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
8. Europe Endothelial Dysfunction Market Analysis – by Test Type
8.1 Overview
8.2 Europe Endothelial Dysfunction Market, By Test Type, 2022 & 2028 (%)
8.3 Invasive Tests
8.3.1 Overview
8.3.2 Invasive Tests: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
8.4 Non-Invasive Tests
8.4.1 Overview
8.4.2 Non-Invasive Tests: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
8.4.3 Flow Mediated Dilatory
8.4.3.1 Overview
8.4.3.2 Flow Mediated Dilatory: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
8.4.4 Venous Occlusion Plethysmography
8.4.4.1 Overview
8.4.4.2 Venous Occlusion Plethysmography: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
8.4.5 Peripheral Arterial Tonometry (PAT)
8.4.5.1 Overview
8.4.5.2 Peripheral Arterial Tonometry (PAT): Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
8.4.6 Circulating Markers
8.4.6.1 Overview
8.4.6.2 Circulating Markers: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
8.4.7 Others
8.4.7.1 Overview
8.4.7.2 Others: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
9. Europe Endothelial Dysfunction Market Analysis – by End User
9.1 Overview
9.2 Europe Endothelial Dysfunction Market, By End User, 2022 & 2028 (%)
9.3 Hospitals
9.3.1 Overview
9.3.2 Hospitals: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
9.4 Diagnostics Centers
9.4.1 Overview
9.4.2 Diagnostics Centers: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
9.5 Clinics
9.5.1 Overview
9.5.2 Clinics: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
9.6 Others
9.6.1 Overview
9.6.2 Others: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
10. Europe Endothelial Dysfunction Market – Revenue and Forecast to 2028 – Country Analysis
10.1 Europe: Endothelial Dysfunction Market
10.1.1 Overview
10.1.1.1 Germany: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.1.1 Overview
10.1.1.1.2 Germany: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.1.3 Germany: Endothelial Dysfunction Market, by Cause, 2020–2028 (US$ Million)
10.1.1.1.4 Germany: Endothelial Dysfunction Market, by Test Type – 2020–2028 (US$ Million)
10.1.1.1.4.1 Germany: Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
10.1.1.1.5 Germany: Endothelial Dysfunction Market, by End User 2020–2028 (US$ Million)
10.1.1.2 UK: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.2.1 Overview
10.1.1.2.2 UK: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.2.3 UK: Endothelial Dysfunction Market, by Cause, 2020–2028 (US$ Million)
10.1.1.2.4 UK: Endothelial Dysfunction Market, by Test Type – 2020–2028 (US$ Million)
10.1.1.2.4.1 UK: Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
10.1.1.2.5 UK: Endothelial Dysfunction Market, by End User 2020–2028 (US$ Million)
10.1.1.3 France: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.3.1 Overview
10.1.1.3.2 France: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.3.3 France: Endothelial Dysfunction Market, by Cause, 2020–2028 (US$ Million)
10.1.1.3.4 France: Endothelial Dysfunction Market, by Test Type – 2020–2028 (US$ Million)
10.1.1.3.4.1 France: Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
10.1.1.3.5 France: Endothelial Dysfunction Market, by End User 2020–2028 (US$ Million)
10.1.1.4 Italy: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.4.1 Overview
10.1.1.4.2 Italy: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.4.3 Italy: Endothelial Dysfunction Market, by Cause, 2020–2028 (US$ Million)
10.1.1.4.4 Italy: Endothelial Dysfunction Market, by Test Type – 2020–2028 (US$ Million)
10.1.1.4.4.1 Italy: Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
10.1.1.4.5 Italy: Endothelial Dysfunction Market, by End User 2020–2028 (US$ Million)
10.1.1.5 Spain: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.5.1 Overview
10.1.1.5.2 Spain: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.5.3 Spain: Endothelial Dysfunction Market, by Cause, 2020–2028 (US$ Million)
10.1.1.5.4 Spain: Endothelial Dysfunction Market, by Test Type – 2020–2028 (US$ Million)
10.1.1.5.4.1 Spain: Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
10.1.1.5.5 Spain: Endothelial Dysfunction Market, by End User 2020–2028 (US$ Million)
10.1.1.6 Rest of Europe: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.6.1 Overview
10.1.1.6.2 Rest of Europe: Endothelial Dysfunction Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.6.3 Rest of Europe: Endothelial Dysfunction Market, by Cause, 2020–2028 (US$ Million)
10.1.1.6.4 Rest of Europe: Endothelial Dysfunction Market, by Test Type – 2020–2028 (US$ Million)
10.1.1.6.4.1 Rest of Europe: Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
10.1.1.6.5 Rest of Europe: Endothelial Dysfunction Market, by End User 2020–2028 (US$ Million)
11. Europe Endothelial Dysfunction Market–Industry Landscape
11.1 Overview
11.2 Growth Strategies in the Endothelial Dysfunction Market
11.3 Inorganic Growth Strategies
11.3.1 Overview
11.4 Organic Growth Strategies
11.4.1 Overview
12. Company Profiles
12.1 ZOLL Medical Corp
12.1.1 Key Facts
12.1.2 Business Description
12.1.3 Products and Services
12.1.4 Financial Overview
12.1.5 SWOT Analysis
12.1.6 Key Developments
12.2 Sphingo Tec GmbH
12.2.1 Key Facts
12.2.2 Business Description
12.2.3 Products and Services
12.2.4 Financial Overview
12.2.5 SWOT Analysis
12.2.6 Key Developments
12.3 The Polymath Co
12.3.1 Key Facts
12.3.2 Business Description
12.3.3 Products and Services
12.3.4 Financial Overview
12.3.5 SWOT Analysis
12.3.6 Key Developments
12.4 SMART Medical Ltd
12.4.1 Key Facts
12.4.2 Business Description
12.4.3 Products and Services
12.4.4 Financial Overview
12.4.5 SWOT Analysis
12.4.6 Key Developments
12.5 Alam Medical SaRl
12.5.1 Key Facts
12.5.2 Business Description
12.5.3 Products and Services
12.5.4 Financial Overview
12.5.5 SWOT Analysis
12.5.6 Key Developments
12.6 Medizinische Messtechnik GmbH
12.6.1 Key Facts
12.6.2 Business Description
12.6.3 Products and Services
12.6.4 Financial Overview
12.6.5 SWOT Analysis
12.6.6 Key Developments
13. Appendix
13.1 About The Insight Partners
13.2 Glossary of Terms

Table 1. Techniques Used in to Assess Endothelial Function
Table 2. Novel Soluble and Cell Component Biomarkers of Endothelia Dysfunction in Cardiovascular Diseases
Table 3. Germany Endothelial Dysfunction Market, by Cause – Revenue and Forecast to 2028 (US$ Million)
Table 4. Germany Endothelial Dysfunction Market, by Test Type – Revenue and Forecast to 2028 (US$ Million)
Table 5. Germany Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
Table 6. Germany Endothelial Dysfunction Market, by End User – Revenue and Forecast to 2028 (US$ Million)
Table 7. UK Endothelial Dysfunction Market, by Cause – Revenue and Forecast to 2028 (US$ Million)
Table 8. UK Endothelial Dysfunction Market, by Test Type – Revenue and Forecast to 2028 (US$ Million)
Table 9. UK Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
Table 10. UK Endothelial Dysfunction Market, by End User – Revenue and Forecast to 2028 (US$ Million)
Table 11. France Endothelial Dysfunction Market, by Cause – Revenue and Forecast to 2028 (US$ Million)
Table 12. France Endothelial Dysfunction Market, by Test Type – Revenue and Forecast to 2028 (US$ Million)
Table 13. France Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
Table 14. France Endothelial Dysfunction Market, by End User – Revenue and Forecast to 2028 (US$ Million)
Table 15. Italy Endothelial Dysfunction Market, by Cause – Revenue and Forecast to 2028 (US$ Million)
Table 16. Italy Endothelial Dysfunction Market, by Test Type – Revenue and Forecast to 2028 (US$ Million)
Table 17. Italy Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
Table 18. Italy Endothelial Dysfunction Market, by End User – Revenue and Forecast to 2028 (US$ Million)
Table 19. Spain Endothelial Dysfunction Market, by Cause – Revenue and Forecast to 2028 (US$ Million)
Table 20. Spain Endothelial Dysfunction Market, by Test Type – Revenue and Forecast to 2028 (US$ Million)
Table 21. Spain Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
Table 22. Spain Endothelial Dysfunction Market, by End User – Revenue and Forecast to 2028 (US$ Million)
Table 23. Rest of Europe Endothelial Dysfunction Market, by Cause – Revenue and Forecast to 2028 (US$ Million)
Table 24. Rest of Europe Endothelial Dysfunction Market, by Test Type – Revenue and Forecast to 2028 (US$ Million)
Table 25. Rest of Europe Endothelial Dysfunction Market, by Non-Invasive Tests – Revenue and Forecast to 2028 (US$ Million)
Table 26. Rest of Europe Endothelial Dysfunction Market, by End User – Revenue and Forecast to 2028 (US$ Million)
Table 27. Recent Inorganic Growth Strategies in the Endothelial Dysfunction Market
Table 28. Recent Organic Growth Strategies in the Endothelial Dysfunction Market
Table 29. Glossary of Terms, Endothelial dysfunction market

Figure 1. Europe Endothelial Dysfunction Market Segmentation
Figure 2. Europe Endothelial Dysfunction Market, by Country
Figure 3. Europe Endothelial Dysfunction Market Overview
Figure 4. Hypertension Account for Largest Share of Cause Segment in Europe Endothelial Dysfunction Market
Figure 5. Germany Expected to Show Remarkable Growth During Forecast Period
Figure 6. Europe: PEST Analysis
Figure 7. Expert Opinion
Figure 8. Europe Endothelial Dysfunction Market: Impact Analysis of Drivers and Restraints
Figure 9. Europe Endothelial Dysfunction Market – Revenue Forecast and Analysis – 2020–2028
Figure 10. Europe Endothelial Dysfunction Market, by Cause, 2022 & 2028 (%)
Figure 11. Hypertension: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 12. Diabetes: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 13. Hypercholestrolaemia: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 14. Behcet’s disease: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 15. Obesity: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 16. Others: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 17. Europe Endothelial Dysfunction Market, by Test Type, 2022 & 2028 (%)
Figure 18. Invasive Tests: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 19. Non-Invasive Tests: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 20. Flow Mediated Dilatory: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 21. Venous Occlusion Plethysmography: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 22. Peripheral Arterial Tonometry (PAT): Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 23. Circulating Markers: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 24. Others: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 25. Europe Endothelial Dysfunction Market, by End User, 2022 & 2028 (%)
Figure 26. Hospitals and Clinics: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 27. Diagnostics Centers: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 28. Clinics: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 29. Others: Europe Endothelial Dysfunction Market Revenue and Forecast to 2028 (US$ Million)
Figure 30. Europe: Endothelial Dysfunction Market, by Key Country – Revenue (2022) (US$ Million)
Figure 31. Europe: Endothelial Dysfunction Market, by Country, 2022 & 2028 (%)
Figure 32. Germany: Endothelial Dysfunction Market – Revenue and Forecast to 2028 (US$ Million)
Figure 33. UK: Endothelial Dysfunction Market – Revenue and Forecast to 2028 (US$ Million)
Figure 34. France: Endothelial Dysfunction Market – Revenue and Forecast to 2028 (US$ Million)
Figure 35. Italy: Endothelial Dysfunction Market – Revenue and Forecast to 2028 (US$ Million)
Figure 36. Spain: Endothelial Dysfunction Market – Revenue and Forecast to 2028 (US$ Million)
Figure 37. Rest of Europe: Endothelial Dysfunction Market – Revenue and Forecast to 2028 (US$ Million)
Figure 38. Growth Strategies in the Endothelial Dysfunction Market