Europe Antibody Drug Conjugates Market Forecast to 2030
Europe Antibody Drug Conjugates Market Forecast to 2030 – Regional Analysis – By Technology (Cleavable Linker and Non-cleavable Linker), Application (Blood Cancer, Breast Cancer, Ovarian Cancer, Urothelial Cancer, and Others), and Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies)
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Description
Increasing Investments to Develop ADCs Fuels the Europe Antibody Drug Conjugates Market
ADCs are a game changer in the field of oncology; these are widely accepted for treating breast cancer. Several companies are making huge investments to develop novel ADCs. In May 2022, Evotec SE announced a huge strategic equity investment in Tubulis GmbH to develop ADCs. Evotec SE has invested US$ 64 million (€ 60 million) during Tublis’s Series B financing round, which is led by Andera Partners. Similarly, in June 2022, Spirea Limited announced that it had received investments of US$ 3 million (£2.4 million) from the UK and the US investors to develop a new generation of ADC.
According to an article, ‘Antibody-Drug Conjugates: Increasing Investment In R&D And Partnership,’ published in February 2023, ~63% of ADC developers would actively seek funds and investments in 2023. While ~34% of ADCs will enter into strategic mergers and acquisitions for ADC developments, nearly 56% of companies will make acquisitions of ADC developers. The investments have created broader opportunities for the Europe antibody drug conjugates market. According to the Hanson Wade Analytics, 57 ADCs entered phase I clinical trials in 2022, accounting for an increase of 20 ADCs from 2021. Moreover, companies are making huge profits through their commercialized products, contributing to market growth for ADCs. For instance, Gilead Sciences, Inc. has gained US$ 22 million in the first quarter of 2023 for its Trodelvy (Sacituzumab govitecan-hziy) that treats HER2-negative metastatic breast cancer. It has experienced an increase of 52% compared to 2022. The increase in profits is also expected to enhance strategic investments and decisions that would expand the market growth shortly.
Europe Antibody Drug Conjugates Market Overview
The Europe antibody drug conjugate market is segmented into the UK, Germany, France, Italy, Spain, and the Rest of Europe. The increasing investments and partnership agreements in ADC development and rising cancer cases are leading to market growth in the region. For instance, in February 2023, the UK-based AstraZeneca and KYM Biosciences Inc. signed a global exclusive license agreement for ADC, CMG901, that targets Claudin. Claudin is a promising therapeutic target in gastric cancer. AstraZeneca will be responsible for researching, developing, and commercializing CMG901 globally. Currently, CMG901 is in phase I clinical trials to study the treatment of Claudin 18.2-positive solid tumors, including gastric cancer. It is estimated that such innovations for ADCs by the players are likely to boost the market growth in the country.
Furthermore, German-based companies are also witnessing collaborations for the development of ADCs. In April 2023, Tubulis, a German Biotech company, collaborated with Bristol Myers Squibb (BMS) to develop effective and safe ADCs to treat solid tumors. Under the strategic license agreement, BMS will access Tubulis’s Tubutecan payloads and P5 conjugation platform. The agreement will likely facilitate the development of stable and safer ADCs. Such strategic developments for the ADCs developments will allow players to increase the number of products and commercialize in the market, contributing to increasing market size.
Europe Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Million)
Europe Antibody Drug Conjugates Market Segmentation
The Europe antibody drug conjugates market is segmented based on technology, application, distribution channel, and country.
Based on technology, the Europe antibody drug conjugates market antibody drug conjugates market is bifurcated into cleavable linker and non-cleavable linker. The cleavable linker segment held a larger share in 2022.
Based on application, the Europe antibody drug conjugates market antibody drug conjugates market is segmented into blood cancer, breast cancer, ovarian cancer, urothelial cancer, and others. The breast cancer segment held the largest share in 2022.
Based on distribution channel, the Europe antibody drug conjugates market antibody drug conjugates market is segmented into hospital pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacies segment held the largest share in 2022.
Based on country, the Europe antibody drug conjugates market is categorized into Germany, France, UK, Italy, Spain, and the Rest of Europe. Germany dominated the Europe antibody drug conjugates market in 2022.
ADC Therapeutics SA, Pfizer Inc, Hoffmann-La Roche Ltd, ImmunoGen, Inc, GSK Plc, Gilead Sciences Inc, AstraZeneca Plc, Astellas Pharma Inc, and Takeda Pharmaceutical Co Ltd are some of the leading companies operating in the Europe antibody drug conjugates market.
Summary Info
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According to the Research Team’ research, the Europe antibody drug conjugates market was valued at US$ 2,263.14 million in 2022 and is expected to reach US$ 7,947.86 million by 2030, registering a CAGR of 17.0% from 2022 to 2030. Rising incidences of cancer cases and growing strategic partnerships to develop antibody drug conjugates are among the critical factors attributed to the Europe antibody drug conjugates market expansion.
Rising cancer incidences are primarily leading to the increasing demand for innovative cancer treatments. As per the Global Cancer Observatory (GLOBOCAN) estimates published in 2020, there were 19.3 million cancer cases across the globe. Similarly, as per the World Health Organization (WHO) data published in February 2022, ~10 million people have died from cancer. The most commonly seen cancer types were lung, breast, colon and rectum, prostate, and breast. The rising incidences of cancer have raised concerns worldwide. Below is the list of common cancer cases reported worldwide in 2020.
Table 1. New Cancer Cases Worldwide, in 2020
Sr. No. Cancer Type Number of Cases (Million)
1 Stomach 1.09
2 Skin (non-melanoma) 1.2
3 Prostate 1.41
4 Colon and Rectum 1.93
5 Lung 2.21
6 Breast 2.26
Cancer is now a lifestyle disease commonly seen among people with unhealthy food habits and who are physically inactive. Also, the consumption of alcohol and tobacco adds up to the risk of developing cancer. Chronic infectious diseases in low- and middle-income countries can further aggravate the cancer risk factors. According to the WHO data published in February 2022, chronic infectious diseases such as human papillomavirus (HPV), Helicobacter pylori, hepatitis B virus, hepatitis C virus, and Epstein-Barr virus attributed to nearly 18% of the diagnosed in 2018. Also, promising results of ADCs are anticipated to accelerate their demand as an effective cancer treatment and propel the market growth.
On the contrary, high cost of ADCs development and commercialization hampers the growth Europe antibody drug conjugates market.
Based on technology, the Europe antibody drug conjugates market is bifurcated into cleavable linker and non-cleavable linker. The cleavable linker segment held 67.9% share of the Europe antibody drug conjugates market in 2022, amassing US$ 1,536.17 million. It is projected to garner US$ 5,327.46 million by 2030 to expand at 16.8% CAGR during 2022-2030.
Based on application, the Europe antibody drug conjugates market is segmented into blood cancer, breast cancer, ovarian cancer, urothelial cancer, and others. The breast cancer segment held 57.3% share of the Europe antibody drug conjugates market in 2022, amassing US$ 1,297.53 million. It is projected to garner US$ 4,690.90 million by 2030 to expand at 17.4% CAGR during 2022-2030.
Based on distribution channel, the Europe antibody drug conjugates market is segmented into hospital pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacies segment held 70.9% share of Europe antibody drug conjugates market in 2022, amassing US$ 1,604.81 million. It is projected to garner US$ 5,771.53 million by 2030 to expand at 17.4% CAGR during 2022-2030.
Based on country, the Europe antibody drug conjugates market is categorized into Germany, France, UK, Italy, Spain, and the Rest of Europe. Germany held 31.7% share of Europe antibody drug conjugates market in 2022, amassing US$ 716.28 million. It is projected to garner US$ 2,658.56 million by 2030 to expand at 17.8% CAGR during 2022-2030.
Key players operating in the Europe antibody drug conjugates market are ADC Therapeutics SA, Pfizer Inc, Hoffmann-La Roche Ltd, ImmunoGen, Inc, GSK Plc, Gilead Sciences Inc, AstraZeneca Plc, Astellas Pharma Inc, and Takeda Pharmaceutical Co Ltd, among others.
– In Mar 2023, Pfizer Inc. and Seagen Inc entered into a definitive merger agreement under which Pfizer will acquire Seagen, a global biotechnology company that discovers, develops, and commercializes transformative cancer medicines, for $229 in cash per Seagen share for a total enterprise value of $43 billion.
– In Sept 2023, Seagen Inc., a world leader and pioneer in antibody-drug conjugate (ADC) therapies, and RemeGen Co., Ltd. have entered into an exclusive worldwide licensing agreement to develop and commercialize disitamab vedotin, a novel HER2-targeted ADC. This collaboration leverages Seagens world-class expertise and knowledge of ADC development, manufacturing, and commercialization to maximize the potential of disitamab vedotin.
o Highlights key business priorities in order to assist companies to realign their business strategies.
o The key findings and recommendations highlight crucial progressive industry trends in Europe antibody drug conjugates market, thereby allowing players across the value chain to develop effective long-term strategies.
o Develop/modify business expansion plans by using substantial growth offering developed and emerging markets.
o Scrutinize in-depth Europe market trends and outlook coupled with the factors driving the market, as well as those hindering it.
o Enhance the decision-making process by understanding the strategies that underpin security interest with respect to client products, segmentation, pricing, and distribution
TABLE OF CONTENTS
1.1 the Research Team Research Report Guidance
1.2 Market Segmentation
2. Executive Summary
2.1 Market Attractiveness
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. Europe Antibody Drug Conjugates Market – Key Industry Dynamics
4.1 Key Market Drivers:
4.1.1 Growing Strategic Partnerships to Develop Antibody Drug Conjugates
4.1.2 Rising Incidences of Cancer Cases
4.1.3 Increasing FDA Approvals for ADCs
4.2 Market Restraints
4.2.1 High Cost of ADCs Development and Commercialization
4.3 Market Opportunities
4.3.1 Increasing Investments to Develop ADCs
4.4 Market Trends
4.4.1 Escalating Pipeline of ADCs
4.5 Impact Analysis:
5. Antibody Drug Conjugates Market – Europe Market Analysis
5.1 Europe Antibody Drug Conjugates Market Revenue (US$ Mn), 2017 – 2030
6. Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 – by Technology
6.1 Overview
6.2 Europe Antibody Drug Conjugates Market Revenue Share, by Technology 2022 & 2030 (%)
6.3 Cleavable Linker
6.3.1 Overview
6.3.2 Cleavable Linker: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
6.4 Non-cleavable Linker
6.4.1 Overview
6.4.2 Non-cleavable Linker: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
7. Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 – by Application
7.1 Overview
7.2 Europe Antibody Drug Conjugates Market Revenue Share, by Application 2022 & 2030 (%)
7.3 Blood Cancer
7.3.1 Overview
7.3.2 Blood Cancer: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
7.4 Breast Cancer
7.4.1 Overview
7.4.2 Breast Cancer: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
7.5 Ovarian Cancer
7.5.1 Overview
7.5.2 Ovarian Cancer: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
7.6 Urothelial Cancer
7.6.1 Overview
7.6.2 Urothelial Cancer: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
7.7 Others
7.7.1 Overview
7.7.2 Others: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
8. Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 – by Distribution Channel
8.1 Overview
8.2 Europe Antibody Drug Conjugates Market Revenue Share, by Distribution Channel 2022 & 2030 (%)
8.3 Hospital Pharmacies
8.3.1 Overview
8.3.2 Hospital Pharmacies: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
8.4 Retail Pharmacies
8.4.1 Overview
8.4.2 Retail Pharmacies: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
8.5 Online Pharmacies
8.5.1 Overview
8.5.2 Online Pharmacies: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
9. Europe Antibody Drug Conjugates Market – Country Analysis
9.1 Europe Antibody Drug Conjugates Market, Revenue and Forecast To 2030
9.1.1 Overview
9.1.2 Europe Antibody Drug Conjugates Market Breakdown, by Country – Revenue (2022) (US$ Million)
9.1.3 Europe: Antibody Drug Conjugates Market, by Country
9.1.3.1 UK
9.1.3.1.1 Overview
9.1.3.1.2 UK: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
9.1.3.1.3 UK: Antibody Drug Conjugates Market, by Technology
9.1.3.1.4 UK: Antibody Drug Conjugates Market, by Application
9.1.3.1.5 UK: Antibody Drug Conjugates Market, by Distribution Channel
9.1.3.2 Germany
9.1.3.2.1 Overview
9.1.3.2.2 Germany: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
9.1.3.2.3 Germany: Antibody Drug Conjugates Market, by Technology
9.1.3.2.4 Germany: Antibody Drug Conjugates Market, by Application
9.1.3.2.5 Germany: Antibody Drug Conjugates Market, by Distribution Channel
9.1.3.3 France
9.1.3.3.1 Overview
9.1.3.3.2 France: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
9.1.3.3.3 France: Antibody Drug Conjugates Market, by Technology
9.1.3.3.4 France: Antibody Drug Conjugates Market, by Application
9.1.3.3.5 France: Antibody Drug Conjugates Market, by Distribution Channel
9.1.3.4 Italy
9.1.3.4.1 Overview
9.1.3.4.2 Italy: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
9.1.3.4.3 Italy: Antibody Drug Conjugates Market, by Technology
9.1.3.4.4 Italy: Antibody Drug Conjugates Market, by Application
9.1.3.4.5 Italy: Antibody Drug Conjugates Market, by Distribution Channel
9.1.3.5 Spain
9.1.3.5.1 Overview
9.1.3.5.2 Spain: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
9.1.3.5.3 Spain: Antibody Drug Conjugates Market, by Technology
9.1.3.5.4 Spain: Antibody Drug Conjugates Market, by Application
9.1.3.5.5 Spain: Antibody Drug Conjugates Market, by Distribution Channel
9.1.3.6 Rest of Europe
9.1.3.6.1 Overview
9.1.3.6.2 Rest of Europe: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
9.1.3.6.3 Rest of Europe: Antibody Drug Conjugates Market, by Technology
9.1.3.6.4 Rest of Europe: Antibody Drug Conjugates Market, by Application
9.1.3.6.5 Rest of Europe: Antibody Drug Conjugates Market, by Distribution Channel
10. Antibody Drug Conjugates Market-Industry Landscape
10.1 Overview
10.2 Organic Growth Strategies
10.2.1 Overview
10.3 Inorganic Growth Strategies
10.3.1 Overview
10.4 Companies’ Manufacturing Capacities and Capabilities
11. Company Profiles
11.1 ADC Therapeutics SA
11.1.1 Key Facts
11.1.2 Business Description
11.1.3 Products and Services
11.1.4 Financial Overview
11.1.5 SWOT Analysis
11.1.6 Key Developments
11.2 Pfizer Inc
11.2.1 Key Facts
11.2.2 Business Description
11.2.3 Products and Services
11.2.4 Financial Overview
11.2.5 SWOT Analysis
11.2.6 Key Developments
11.3 Hoffmann-La Roche Ltd
11.3.1 Key Facts
11.3.2 Business Description
11.3.3 Products and Services
11.3.4 Financial Overview
11.3.5 SWOT Analysis
11.3.6 Key Developments
11.4 ImmunoGen, Inc.
11.4.1 Key Facts
11.4.2 Business Description
11.4.3 Products and Services
11.4.4 Financial Overview
11.4.5 SWOT Analysis
11.4.6 Key Developments
11.5 GSK Plc
11.5.1 Key Facts
11.5.2 Business Description
11.5.3 Products and Services
11.5.4 Financial Overview
11.5.5 SWOT Analysis
11.5.6 Key Developments
11.6 Gilead Sciences Inc
11.6.1 Key Facts
11.6.2 Business Description
11.6.3 Products and Services
11.6.4 Financial Overview
11.6.5 SWOT Analysis
11.6.6 Key Developments
11.7 AstraZeneca Plc
11.7.1 Key Facts
11.7.2 Business Description
11.7.3 Products and Services
11.7.4 Financial Overview
11.7.5 SWOT Analysis
11.7.6 Key Developments
11.8 Astellas Pharma Inc
11.8.1 Key Facts
11.8.2 Business Description
11.8.3 Products and Services
11.8.4 Financial Overview
11.8.5 SWOT Analysis
11.8.6 Key Developments
11.9 Takeda Pharmaceutical Co Ltd
11.9.1 Key Facts
11.9.2 Business Description
11.9.3 Products and Services
11.9.4 Financial Overview
11.9.5 SWOT Analysis
11.9.6 Key Developments
12. Appendix
12.1 About Us
12.2 Glossary of Terms
LIST OF TABLES
Table 1. Europe Antibody Drug Conjugates Market Segmentation
Table 2. New Cancer Cases Worldwide, in 2020
Table 3. List of FDA-Approved ADCs
Table 4. UK: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Technology
Table 5. UK: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Application
Table 6. UK: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Distribution Channel
Table 7. Germany: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Technology
Table 8. Germany: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Application
Table 9. Germany: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Distribution Channel
Table 10. France: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Technology
Table 11. France: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Application
Table 12. France: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Distribution Channel
Table 13. Italy: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Technology
Table 14. Italy: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Application
Table 15. Italy: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Distribution Channel
Table 16. Spain: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Technology
Table 17. Spain: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Application
Table 18. Spain: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Distribution Channel
Table 19. Rest of Europe: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Technology
Table 20. Rest of Europe: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Application
Table 21. Rest of Europe: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn) – Distribution Channel
Table 22. Recent Organic Growth Strategies in Antibody Drug Conjugates Market
Table 23. Recent Inorganic Growth Strategies in the Antibody Drug Conjugates Market
Table 24. Glossary of Terms, Antibody Drug Conjugates Market
LIST OF FIGURES
Figure 1. Europe Antibody Drug Conjugates Market Segmentation, By Country
Figure 2. Key Insights
Figure 3. Europe Antibody Drug Conjugates Market – Key Industry Dynamics
Figure 4. Impact Analysis of Drivers and Restraints
Figure 5. Europe Antibody Drug Conjugates Market Revenue (US$ Mn), 2017 – 2030
Figure 6. Europe Antibody Drug Conjugates Market Revenue Share, by Technology 2022 & 2030 (%)
Figure 7. Cleavable Linker: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 8. Non-Cleavable Linker: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 9. Europe Antibody Drug Conjugates Market Revenue Share, by Application 2022 & 2030 (%)
Figure 10. Blood Cancer: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 11. Breast Cancer: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 12. Ovarian Cancer: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 13. Urothelial Cancer: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 14. Others: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 15. Europe Antibody Drug Conjugates Market Revenue Share, by Distribution Channel 2022 & 2030 (%)
Figure 16. Hospital Pharmacies: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 17. Retail Pharmacies: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 18. Online Pharmacies: Europe Antibody Drug Conjugates Market – Revenue and Forecast to 2030 (US$ Million)
Figure 19. Europe Antibody Drug Conjugates, by Key Country – Revenue (2022) (US$ Million)
Figure 20. Europe: Antibody Drug Conjugates Market, By Key Countries, 2022 And 2030 (%)
Figure 21. UK: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
Figure 22. Germany: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
Figure 23. France: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
Figure 24. Italy: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
Figure 25. Spain: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
Figure 26. Rest of Europe: Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Mn)
The List of Companies – Europe Antibody Drug Conjugates Market
1. ADC Therapeutics SA
2. Pfizer Inc
3. Hoffmann-La Roche Ltd
4. ImmunoGen, Inc
5. GSK Plc
6. Gilead Sciences Inc
7. AstraZeneca Plc
8. Astellas Pharma Inc
9. Takeda Pharmaceutical Co Ltd
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