Asia Pacific T Cell Therapy Market Forecast to 2030
Asia Pacific T Cell Therapy Market Forecast to 2030 – Regional Analysis – by Modality (Research and Commercialized), Therapy Type [CAR T-cell Therapy and T-cell Receptor (TCR)-based], and Indication (Hematologic Malignancies and Solid Tumors)
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Description
Increasing Number of T-Cell Therapy Approvals Fuels the Asia Pacific T Cell Therapy Market
Targeted treatment, faster and more efficient recovery, and reduced side effects are among the advantages of t cell therapy. Globally, cell therapies are widely adopted owing to the availability of various approvals. For instance, in 2023: Janssen’s CAR-T cell therapy CARVYKTI (Ciltacabtagene Autoleucel) has been approved as a fourth-line treatment for multiple myeloma patients by the Therapeutic Goods Administration, Australia.
In 2023: The Chinese National Medical Products Administration has approved the use of Fucaso (equecabtagene autoleucel) by Innovent Biologics and IASO Biotechnology (IASO Bio) for the treatment of adult patients with relapsed or refractory multiple myeloma (RRMM). In June 2023, the agency approved the therapy’s new drug application (NDA).
In 2023: The first humanized CD19-targeted Chimeric Antigen Receptor T cell (CAR-T cell) therapy product, NexCAR19 (Actalycabtagene autoleucel), has been approved by the Central Drugs Standard Control Organization (CDSO) for use in cases of relapsed/refractory B-cell lymphomas and leukemia in India. Immuno Adoptive Cell Therapy is incubated at IIT Bombay.
In 2023: Yikaida (axicabtagene ciloleucel), an autologous CAR T-cell therapy developed by Fosun Kite Biotechnology, was granted approval by China’s National Medical Products Administration (NMPA) for use as a second-line treatment for patients with large B-cell lymphoma.
In 2020: The Ministry of Health, Labor and Welfare (MHLW) of Japan has granted the Foundation for Biomedical Research and Innovation at Kobe (“FBRI”) a marketing license to produce and distribute Kymriah (tisagenlecleucel) for patients in Japan. Novartis made this announcement today. With this clearance, FBRI is now the only authorized commercial manufacturing facility in Asia for CAR-T cell therapy.
Thus, the increasing number of approvals for T-cell therapy is fueling the market growth.
Asia Pacific T Cell Therapy Market Overview
The Asia Pacific T-cell therapy market is segmented into China, Japan, India, South Korea, Australia, and the Rest of Asia Pacific. The market in Asia Pacific is expected to witness significant growth as CAR T-cell therapy is efficient in treating cancer, elevating the market growth in the region. Many clinical trials for CAR T-cell therapy are ongoing in the region, offering new opportunities in APAC. China is the largest country in the world for CAR T-cell clinical trials, which hospitals conduct. The CAR-T industry chain is being formed in China, including ongoing and expected regulatory reforms to benefit access to such novel therapies. China approved its first CAR T-cell therapy, relmacabtagene autoleucel of JW Therapeutics, in September 2021 for the treatment of adult patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) after two or more lines of systemic therapy.
Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
Asia Pacific T Cell Therapy Market Segmentation
The Asia Pacific T cell therapy market is segmented into modality , therapy type, indication, and country.
Based on modality, the Asia Pacific T cell therapy market is bifurcated into research and commercialized. The commercialized segment held a larger market share in 2022.
Based on therapy type, the Asia Pacific T cell therapy market is divided into CAR T-cell therapy and T-cell Receptor (TCR)-based. The CAR T-cell therapy segment held a larger market share in 2022.
Based on indication, the Asia Pacific T cell therapy market is bifurcated into hematologic malignancies and solid tumors. The hematologic malignancies segment held the largest market share in 2022.
Based on country, the Asia Pacific T cell therapy market is segmented into China, Japan, Australia, South Korea, and the Rest of Asia Pacific. China dominated the Asia Pacific T cell therapy market in 2022.
Bristol-Myers Squibb Co, Gilead Sciences Inc, Innovent Biologics Inc, Janssen Global Services LLC, JW (Cayman) Therapeutics Co Ltd, Legend Biotech Corp, and Novartis AG are some of the leading companies operating in the Asia Pacific T cell therapy market.
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According to the research team’ research, the Asia Pacific T cell therapy market was valued at US$ 251.99 million in 2022 and is expected to reach US$ 882.72 million by 2030, registering a CAGR of 17.0% from 2022 to 2030. Growing burden of cancer worldwide and increasing number of approvals of t-cell therapies are among the critical factors attributed to the Asia Pacific T cell therapy market expansion.
The current landscape for CAR T-cell therapies across the globe is promising, with multiple drug approvals, a rich pipeline, and many ongoing clinical trials. Pipelines of CAR T-cell therapies are in various stages of clinical development; major pharmaceutical companies are working to advance the pipeline space and future growth potential of the CAR T-cell therapy competitive domain.
In November 2022, Peter MacCallum Cancer Centre and Cartherics Pty Ltd entered into a Collaborative Development Program Agreement (CDPA) to develop Cartherics’ proprietary autologous CAR T cell therapy (CTH-001) for treating cutaneous T-cell lymphoma (CTCL). The key aspects of the collaborative research are setting up clinical-scale manufacturing of CTH-001 and conducting a Phase I clinical trial. It will initially enroll six patients with refractory CTCL. JW Therapeutics drug JWCAR029 is a CAR T cell product that targets CD19 and is intended to treat advanced lymphoma and leukemia. The molecule is currently in Phase II of development. JWCAR029 is initially being investigated for treating B-cell malignancies, focusing on relapsed and refractory DLBCL. Gilead Sciences drug KTE-X19 is an autologous CD19 CAR T-cell therapy under investigation. The drug is manufactured using the XLP process, including T-cell selection and lymphocyte enrichment. Lymphocyte enrichment is required in certain B-cell malignancies for which KTE-X19 is being studied. KTE-X19 is currently in Phase II clinical trials for the treatment of both adult and pediatric acute lymphocytic leukemia. The FDA has approved Brexucabtagene autoleucel (formerly KTE-X19; Tecartus) for treating adult patients with relapsed or refractory mantle cell lymphoma (MCL). ZUMA-3 is a Phase 1/2 study evaluating KTE-X19, an autologous anti-CD19 CAR T-cell therapy, in adult relapsed/refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL). Descartes-11, a mRNA CAR T-cell therapy, has moved into a Phase II clinical trial for newly diagnosed, high-risk multiple myeloma (MM) patients. Descartes-11 expresses CAR T-cell molecules transiently and avoids some characteristic toxicities of these therapeutic agents. A Phase I study (NCT03994705) of 18 patients has already been undertaken, and results showed no evidence of cytokine release syndrome or neurotoxicity—adverse events commonly associated with CAR T-cell treatment. Thus, the pipelines above for CAR T-cell therapies are emerging as a new trend in the Asia Pacific T-cell therapy market.
On the contrary, side-effects of CAR T-cell therapy hampers on the growth of Asia Pacific T cell therapy market.
Based on modality, the Asia Pacific T cell therapy market is bifurcated into research and commercialized. The commercialized segment held 89.8% market share in 2022, amassing US$ 226.31 million. It is projected to garner US$ 810.34 million by 2030 to expand at 17.3% CAGR during 2022-2030.
Based on therapy type, the Asia Pacific T cell therapy market is divided into CAR T-cell therapy and T-cell Receptor (TCR)-based. The CAR T-cell therapy segment held 99.7% share of Asia Pacific T cell therapy market in 2022, amassing US$ 251.23 million. It is projected to garner US$ 881.54 million by 2030 to expand at 17.0% CAGR during 2022-2030.
Based on indication, the Asia Pacific T cell therapy market is bifurcated into hematologic malignancies and solid tumors. The hematologic malignancies segment held 99.7% share of Asia Pacific T cell therapy market in 2022, amassing US$ 251.23 million. It is projected to garner US$ 881.54 million by 2030 to expand at 17.0% CAGR during 2022-2030.
Based on country, the Asia Pacific T cell therapy market has been categorized into China, Japan, Australia, South Korea, and the Rest of Asia Pacific. Our regional analysis states that China captured 36.0% share of Asia Pacific T cell therapy market in 2022. It was assessed at US$ 90.66 million in 2022 and is likely to hit US$ 329.83 million by 2030, exhibiting a CAGR of 17.5% during 2022-2030.
Key players operating in the Asia Pacific T cell therapy market are Bristol-Myers Squibb Co, Gilead Sciences Inc, Innovent Biologics Inc, Janssen Global Services LLC, JW (Cayman) Therapeutics Co Ltd, Legend Biotech Corp, and Novartis AG, among others.
May 2023: Janssen Biotech, Inc. has collaborated with Cellular Biomedicine Group Inc. (CBMG) to develop, manufacture, and commercialize next-generation chimeric antigen receptor (CAR) T-cell therapies for the treatment of B-cell malignancies. These investigational CD20-directed autologous CAR-Ts have demonstrated promising overall and complete response rates in Phase 1 studies in patients with relapsed/refractory non-Hodgkin’s lymphoma (NHL) in China, with the majority of study participants having diffuse large B-cell lymphoma (DLBCL), the most common type of aggressive lymphoma accounting for approximately one-third of B-cell lymphomas globally.
o Save and reduce time carrying out entry-level research by identifying the growth, size, leading players, and segments in the Asia Pacific T cell therapy market
o Highlights key in order to assist companies to realign their business strategies.
o The key findings and recommendations highlight crucial progressive industry trends in Asia Pacific T cell therapy market , thereby allowing players across the value chain to develop effective long-term strategies.
o Develop/modify business expansion plans by using substantial growth offering developed and emerging markets.
o Scrutinize in-depth Asia Pacific market trends and outlook coupled with the factors driving the market, as well as those hindering it.
o Enhance the decision-making process by understanding the strategies that underpin security interest with respect to client products, segmentation, pricing and distribution.
TABLE OF CONTENTS
1. Introduction
1.1 The Research Team Report Guidance
1.2 Market Segmentation
2. Executive Summary
2.1 Key Insights
2.2 Asia Pacific T Cell Therapy Market, by Country (US$ Million)
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. Asia Pacific T Cell Therapy Market – Key Industry Dynamics
4.1 Market Drivers:
4.1.1 Growing Burden of Cancer Worldwide
4.1.2 Increasing Number of T-Cell Therapy Approvals
4.2 Market Restraints
4.2.1 Side-effects of CAR T-Cell Therapy
4.3 Market Opportunities
4.3.1 Growing Investment in T-Cell Therapy
4.4 Future Trends
4.4.1 Rising Number of CAR T-Cell Therapies in Clinical Trials
4.5 Impact Analysis:
5. T Cell Therapy Market – Asia Pacific Market Analysis
5.1 Asia Pacific T Cell Therapy Market Revenue (US$ Mn), 2022 – 2030
6. Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 – by Modality.
6.1 Overview
6.2 Asia Pacific T Cell Therapy Market Revenue Share, by Modality, 2022 & 2030 (%)
6.3 Research
6.3.1 Overview
6.3.2 Research: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
6.4 Commercialized
6.4.1 Overview
6.4.2 Commercialized: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
7. Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 – by Therapy Type
7.1 Overview
7.2 Asia Pacific T Cell Therapy Market Revenue Share, by Therapy Type 2022 & 2030 (%)
7.3 CAR T-cell Therapy
7.3.1 Overview
7.3.2 CAR T-cell Therapy: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
7.4 T-cell Receptor (TCR)-based.
7.4.1 Overview
7.4.2 T-cell Receptor (TCR)-based: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
8. Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 – by Indication.
8.1 Overview
8.2 Asia Pacific T Cell Therapy Market Revenue Share, by Indication, 2022 & 2030 (%)
8.3 Hematologic Malignancies
8.3.1 Overview
8.3.2 Hematologic Malignancies: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
8.3.3 Asia Pacific T Cell Therapy Market, by Haematological Malignancies, 2020-2030 (US$ Million)
8.4 Solid Tumor
8.4.1 Overview
8.4.2 Solid Tumor: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
9. Asia Pacific T Cell Therapy Market – Country Analysis
9.1 Overview
9.1.1.1 Asia Pacific T Cell Therapy Market, by Country
9.1.1.2 China
9.1.1.2.1 China: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
9.1.1.2.2 China: Asia Pacific T Cell Therapy Market, by Modality, 2020-2030 (US$ Million)
9.1.1.2.3 China: Asia Pacific T Cell Therapy Market, by Therapy Type, 2020-2030 (US$ Million)
9.1.1.2.4 China: Asia Pacific T Cell Therapy Market, by Indication, 2020-2030 (US$ Million)
9.1.1.2.4.1 China: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication, 2020-2030 (US$ Million)
9.1.1.3 Japan
9.1.1.3.1 Japan: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
9.1.1.3.2 Japan: Asia Pacific T Cell Therapy Market, by Modality, 2020-2030 (US$ Million)
9.1.1.3.3 Japan: Asia Pacific T Cell Therapy Market, by Therapy Type, 2020-2030 (US$ Million)
9.1.1.3.4 Japan: Asia Pacific T Cell Therapy Market, by Indication, 2020-2030 (US$ Million)
9.1.1.3.4.1 Japan: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication, 2020-2030 (US$ Million)
9.1.1.4 Australia
9.1.1.4.1 Australia: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
9.1.1.4.2 Australia: Asia Pacific T Cell Therapy Market, by Modality, 2020-2030 (US$ Million)
9.1.1.4.3 Australia: Asia Pacific T Cell Therapy Market, by Therapy Type, 2020-2030 (US$ Million)
9.1.1.4.4 Australia: Asia Pacific T Cell Therapy Market, by Indication, 2020-2030 (US$ Million)
9.1.1.4.4.1 Australia: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication, 2020-2030 (US$ Million)
9.1.1.5 South Korea
9.1.1.5.1 South Korea: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
9.1.1.5.2 South Korea: Asia Pacific T Cell Therapy Market, by Modality, 2020-2030 (US$ Million)
9.1.1.5.3 South Korea: Asia Pacific T Cell Therapy Market, by Therapy Type, 2020-2030 (US$ Million)
9.1.1.5.4 South Korea: Asia Pacific T Cell Therapy Market, by Indication, 2020-2030 (US$ Million)
9.1.1.5.4.1 South Korea: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication, 2020-2030 (US$ Million)
9.1.1.6 Rest of Asia Pacific
9.1.1.6.1 Rest of Asia Pacific: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
9.1.1.6.2 Rest of Asia Pacific: Asia Pacific T Cell Therapy Market, by Modality, 2020-2030 (US$ Million)
9.1.1.6.3 Rest of Asia Pacific: Asia Pacific T Cell Therapy Market, by Therapy Type, 2020-2030 (US$ Million)
9.1.1.6.4 Rest of Asia Pacific: Asia Pacific T Cell Therapy Market, by Indication, 2020-2030 (US$ Million)
9.1.1.6.4.1 Rest of Asia Pacific: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication, 2020-2030 (US$ Million)
10. T Cell Therapy Market-Industry Landscape
10.1 Overview
10.2 Growth Strategies in T Cell Therapy Market
10.3 Organic Growth Strategies
10.3.1 Overview
10.4 Inorganic Growth Strategies
10.4.1 Overview
11. Company Profiles
11.1 Legend Biotech Corp
11.1.1 Key Facts
11.1.2 Business Description
11.1.3 Products and Services
11.1.4 Financial Overview
11.1.5 SWOT Analysis
11.1.6 Key Developments
11.2 Janssen Global Services LLC
11.2.1 Key Facts
11.2.2 Business Description
11.2.3 Products and Services
11.2.4 Financial Overview
11.2.5 SWOT Analysis
11.2.6 Key Developments
11.3 Gilead Sciences Inc
11.3.1 Key Facts
11.3.2 Business Description
11.3.3 Products and Services
11.3.4 Financial Overview
11.3.5 SWOT Analysis
11.3.6 Key Developments
11.4 Bristol-Myers Squibb Co
11.4.1 Key Facts
11.4.2 Business Description
11.4.3 Products and Services
11.4.4 Financial Overview
11.4.5 SWOT Analysis
11.4.6 Key Developments
11.5 Novartis AG
11.5.1 Key Facts
11.5.2 Business Description
11.5.3 Products and Services
11.5.4 Financial Overview
11.5.5 SWOT Analysis
11.5.6 Key Developments
11.6 JW (Cayman) Therapeutics Co Ltd
11.6.1 Key Facts
11.6.2 Business Description
11.6.3 Products and Services
11.6.4 Financial Overview
11.6.5 SWOT Analysis
11.6.6 Key Developments
11.7 Innovent Biologics Inc
11.7.1 Key Facts
11.7.2 Business Description
11.7.3 Products and Services
11.7.4 Financial Overview
11.7.5 SWOT Analysis
11.7.6 Key Developments
12. Appendix
12.1 About Us
12.2 Glossary of Terms
LIST OF TABLES
Table 1. Asia Pacific T Cell Therapy Market Segmentation
Table 2. Asia Pacific T Cell Therapy Market, by Hematological Malignancies – Revenue and Forecast to 2030 (US$ Million)
Table 3. FDA-Approved Autologous CAR T-Cell Therapies Registered in Asia Pacific
Table 4. China: Asia Pacific T Cell Therapy Market, by Modality – Revenue and Forecast to 2030 (US$ Million)
Table 5. China: Asia Pacific T Cell Therapy Market, by Therapy Type – Revenue and Forecast to 2030 (US$ Million)
Table 6. China: Asia Pacific T Cell Therapy Market, by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 7. China: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 8. Japan: Asia Pacific T Cell Therapy Market, by Modality – Revenue and Forecast to 2030 (US$ Million)
Table 9. Japan: Asia Pacific T Cell Therapy Market, by Therapy Type – Revenue and Forecast to 2030 (US$ Million)
Table 10. Japan: Asia Pacific T Cell Therapy Market, by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 11. Japan: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 12. Australia: Asia Pacific T Cell Therapy Market, by Modality – Revenue and Forecast to 2030 (US$ Million)
Table 13. Australia: Asia Pacific T Cell Therapy Market, by Therapy Type – Revenue and Forecast to 2030 (US$ Million)
Table 14. Australia: Asia Pacific T Cell Therapy Market, by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 15. Australia: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 16. South Korea: Asia Pacific T Cell Therapy Market, by Modality – Revenue and Forecast to 2030 (US$ Million)
Table 17. South Korea: Asia Pacific T Cell Therapy Market, by Therapy Type – Revenue and Forecast to 2030 (US$ Million)
Table 18. South Korea: Asia Pacific T Cell Therapy Market, by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 19. South Korea: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 20. Rest of Asia Pacific: Asia Pacific T Cell Therapy Market, by Modality – Revenue and Forecast to 2030 (US$ Million)
Table 21. Rest of Asia Pacific: Asia Pacific T Cell Therapy Market, by Therapy Type – Revenue and Forecast to 2030 (US$ Million)
Table 22. Rest of Asia Pacific: Asia Pacific T Cell Therapy Market, by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 23. Rest of Asia Pacific: Asia Pacific T Cell Therapy Market, For Hematologic Malignancies by Indication – Revenue and Forecast to 2030 (US$ Million)
Table 24. Recent Organic Growth Strategies in Asia Pacific T Cell Therapy Market
Table 25. Recent Inorganic Growth Strategies in the Asia Pacific T Cell Therapy Market
Table 26. Glossary of Terms, Asia Pacific T Cell Therapy Market
LIST OF FIGURES
Figure 1. Asia Pacific T Cell Therapy Market Segmentation, By Country
Figure 2. Asia Pacific T Cell Therapy Market – Key Industry Dynamics
Figure 3. Impact Analysis of Drivers and Restraints
Figure 4. Asia Pacific T Cell Therapy Market Revenue (US$ Mn), 2022 – 2030
Figure 5. Asia Pacific T Cell Therapy Market Revenue Share, by Modality, 2022 & 2030 (%)
Figure 6. Research: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
Figure 7. Commercialized: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
Figure 8. Asia Pacific T Cell Therapy Market Revenue Share, by Therapy Type 2022 & 2030 (%)
Figure 9. CAR T-cell Therapy: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
Figure 10. T-cell Receptor (TCR)-based: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
Figure 11. Asia Pacific T Cell Therapy Market Revenue Share, by Indication, 2022 & 2030 (%)
Figure 12. Hematologic Malignancies: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
Figure 13. Solid Tumor: Asia Pacific T Cell Therapy Market – Revenue and Forecast to 2030 (US$ Million)
Figure 14. Asia Pacific T Cell Therapy Market, by Key Country – Revenue, 2022 (US$ Million)
Figure 15. Asia Pacific T Cell Therapy Market, By Key Countries, 2022 and 2030 (%)
Figure 16. China: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
Figure 17. Japan: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
Figure 18. Australia: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
Figure 19. South Korea: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
Figure 20. Rest of Asia Pacific: Asia Pacific T Cell Therapy Market Revenue and Forecast to 2030 (US$ Mn)
Figure 21. Growth Strategies in T Cell Therapy Market
The List of Companies – Asia Pacific T Cell Therapy Market
1. Bristol-Myers Squibb Co
2. Gilead Sciences Inc
3. Innovent Biologics Inc
4. Janssen Global Services LLC
5. JW (Cayman) Therapeutics Co Ltd
6. Legend Biotech Corp
7. Novartis AG
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