North America Bioreactors Market Forecast to 2030
North America Bioreactors Market Forecast to 2030 – Regional Analysis – by Scale (Lab-Scale Production, Pilot-Scale Production, and Full-Scale Production), Application (Microbial Application, Cell Culture Application, and Others), Technology (Fed-Batch Bioreactors and Perfusion Bioreactors), and End User (Biopharma Manufacturers, Research and Development Organizations, and Contract Manufacturing Organization)
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Description
Increasing Adoption of Single-Use Bioreactors Fuels North America Bioreactors Market
Various manufacturers are developing single-use bioreactors (SUBs) as they are robust and provide the high performance required for commercial manufacturing of biopharmaceuticals. Advantages such as film technologies, stirring mechanisms, bioreactor designs, and sensor systems have contributed toward increasing the adoption of disposable reactors from the lab to the production scale. The single-use bioreactors provide next-generation cell and gene therapies and continuous bioprocessing. The advancements in cell-culture processes have developed higher titers and cell densities, which have facilitated the adoption of SUBs.
Single-use bioreactors reduce the risks of contamination and decrease production turnaround times. In the last few years, the use of single-use bioreactors has increased in modern biopharmaceutical processes owing to their unique ability to enhance flexibility, reduce investment, and limit operational costs. Also, many companies have developed single-use bioreactors for producing a wide range of therapeutics. For instance, in March 2021, Thermo Fischer Scientific launched the 3,000 L and 5,000 L HyPerforma DynaDrive single-use bioreactors.
The reduction in validation time has been one of the essential benefits of single-use bioreactors. The rising adoption of single-use bioreactors for upstream bioprocessing is driving the market growth. For instance, Sartorius AG offers a wide range of single-use bioreactors. The company provides ambr 15 for a 10–15 mL micro bioreactor scale and Biostat STR for 50–2000L. The increasing acceptance of single-use bioreactors for the production of therapeutics is driving the market for bioreactors.
North America Bioreactors Market Overview
The US is the largest market for bioreactors—several market players in the US manufacture bioreactors for various applications in pharmaceutical and biotechnology companies. Launch of new bioreactors, geographical expansion, and partnerships by market players drive the growth of the market. In April 2023, BioMADE announced five new projects focused on addressing the research and adoption gaps in bioindustrial manufacturing in the US by advancing bioreactor technology. With a funding commitment of US$ 10.5 million, these projects would span engineering, hardware development, and scalability to address the barriers to accelerate a robust economy. These projects focus on innovation and will advance the design and development of bioreactors, supported by Schmidt Futures. In April 2023, Cytiva launched X-platform bioreactors to simplify upstream bioprocessing operations with single-use products. Initially, available sizes of bioreactors were 50 and 200L. However, the X-Platform bioreactors are equipped with Figurate automation solution software and can increase process efficiency through ergonomic improvements, production capacity, and simplified supply chain operations.
North America Bioreactors Market Revenue and Forecast to 2030 (US$ Million)
North America Bioreactors Market Segmentation
The North America bioreactors market is segmented based on scale, application, technology, end user, and country. Based on scale, the North America bioreactors market is segmented into lab-scale production, pilot-scale production, and full-scale production. The pilot-scale production segment held the largest market share in 2022.
In terms of application, the North America bioreactors market is segmented into microbial application, cell culture application, and others. The cell culture application segment held the largest market share in 2022.
By technology, the North America bioreactors market is bifurcated into fed-batch bioreactors and perfusion bioreactors. The fed-batch bioreactors segment held a larger market share in 2022.
Based on end user, the North America bioreactors market is categorized into biopharma manufacturers, research and development organizations, and contract manufacturing organization. The research and development organizations segment held the largest market share in 2022.
Based on country, the North America bioreactors market is segmented into the US, Canada, and Mexico. The US dominated the North America bioreactors market share in 2022.
PBS Biotech Inc, General Electric Co, Merck KGaA, Thermo Fisher Scientific Inc, Sartorius AG, Pall Corp, Solaris Biotechnology SRL, and Applikon Biotechnology BV are some of the leading players operating in the North America bioreactors market.
Summary Info
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According to the Research Team’ research, the North America bioreactors market was valued at US$ 1,575.60 million in 2022 and is expected to reach US$ 2,669.00 million by 2030, registering a CAGR of 6.8% from 2022 to 2030. Rapid growth of pharmaceutical & biotechnology industry and rising demand for personalized medicine are among the critical factors attributed to the North America bioreactors market expansion.
In recent years, the pharmaceutical industry has been growing at an unprecedented pace. Big pharmaceutical companies and contract research organizations (CROs) are coming up with new medicines and therapy forms to treat a wide range of indications. The biopharmaceuticals market is increasing. The strong demand for biologics and biosimilars has driven the growth of the industry. The biopharmaceutical industry is one of the most significant contributors to the economy. The US is the largest market for biopharmaceuticals and leader in biopharmaceutical R&D. As per the Pharmaceutical Research and Manufacturers Association (PhRMA), the US firms conduct over half the world’s R&D in pharmaceuticals (US$ 75 billion) and holds the highest number of patents in new medicines. Factors such as increasing biologics approval, growing biosimilar pipeline, and rising investment in research activities are facilitating the growth of the industry. Apart from this, increasing approvals in gene and cell therapies are favoring market growth. The approved gene therapies are Glybera-used to treat Lipoprotein Lipase Deficiency and Strimvelis- treating ADA-Severe Combined Immuno Deficiency. Thus, the factors mentioned above are increasing the demand for the large-scale production of various therapeutics, thereby facilitating the growth of the bioreactors market globally.
On the contrary, stringent regulatory framework hurdles the growth of North America bioreactors market.
Based on scale, the North America bioreactors market is categorized into lab-scale production, pilot-scale production, and full-scale production. The pilot-scale production segment held 48.5% share of North America bioreactors market in 2022, amassing US$ 763.87 million. It is projected to garner US$ 1,276.16 million by 2030 to expand at 6.6% CAGR during 2022–2030.
In terms of application, the North America bioreactors market is segmented into microbial application, cell culture application, and others. The cell culture application segment held 48.7% share of North America bioreactors market in 2022, amassing US$ 767.82 million. It is projected to garner US$ 1,276.89 million by 2030 to expand at 6.6% CAGR during 2022–2030.
By technology, the North America bioreactors market is bifurcated into fed-batch bioreactors and perfusion bioreactors. The fed-batch bioreactors segment held 62.1% share of North America bioreactors market in 2022, amassing US$ 978.61 million. It is projected to garner US$ 1,581.12 million by 2030 to expand at 6.2% CAGR during 2022–2030.
Based on end user, the North America bioreactors market is segmented into biopharma manufacturers, research and development organizations, and contract manufacturing organization. The research and development organizations segment held 60.4% share of North America bioreactors market in 2022, amassing US$ 952.15 million. It is projected to garner US$ 1,695.88 million by 2030 to expand at 7.5% CAGR during 2022–2030.
Based on country, the North America bioreactors market has been categorized into the US, Canada, and Mexico. Our regional analysis states that the US captured 87.3% share of North America bioreactors market in 2022. It was assessed at US$ 1,374.71 million in 2022 and is likely to hit US$ 2,371.94 million by 2030, exhibiting a CAGR of 5.8% during 2022–2030.
Key players operating in the North America bioreactors market are PBS Biotech Inc, General Electric Co, Merck KGaA, Thermo Fisher Scientific Inc, Sartorius AG, Pall Corp, Solaris Biotechnology SRL, and Applikon Biotechnology BV, among others.
In July 2023, PBS Biotech Inc and Stemcell Technologies Inc have entered into a supply arrangement that will enable researchers to access PBS-MINI Bioreactors. Through this partnership, PBS will support researchers who wish to grow their cultures of human pluripotent stem cells, or hPSCs, which are essential for drug discovery, disease modeling, future cell-based therapeutics, and pharmaceutical applications. In December 2022, Merck KGaA announced the acquisition of Erbi Biosystems, a developer of 2 ml micro-bioreactor platform technology. The acquisition has allowed Merck KGaA to incorporate Erbi Biosystems’s bioreactor, Breez, into its portfolio and strengthen its therapeutic proteins portfolio. After the acquisition, Merck KGaA aims to increase its Group sales to approximately US$ 26.7 billion (€ 25 billion) by 2025.
o Highlights key business priorities in order to assist companies to realign their business strategies.
o The key findings and recommendations highlight crucial progressive industry trends in the North America bioreactors market, thereby allowing players across the value chain to develop effective long-term strategies.
o Develop/modify business expansion plans by using substantial growth offering developed and emerging markets.
o Scrutinize in-depth North America market trends and outlook coupled with the factors driving the North America bioreactors market, as well as those hindering it.
o Enhance the decision-making process by understanding the strategies that underpin commercial interest with respect to client products, segmentation, pricing, and distribution.
TABLE OF CONTENTS
1. Introduction
1.1 the Research Team Research Report Guidance
1.2 Market Segmentation
2. Executive Summary
2.1 Key Insights
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. North America Bioreactors Market – Key Industry Dynamics
4.1 Bioreactors Market – Key Industry Dynamics
4.2 Market Drivers
4.2.1 Increasing Adoption of Single-Use Bioreactors
4.2.2 Rapid Growth of Pharmaceutical and Biotechnology Industry
4.3 Market Restraints
4.3.1 Stringent Regulatory Framework
4.4 Market Opportunities
4.4.1 Rising Demand for Personalized Medicine
4.5 Future Trends
4.5.1 Technological Advancements in Bioreactors
4.6 Impact of Drivers and Restraints:
5. Bioreactors Market – North America Market Analysis
5.1 Overview
5.2 Bioreactors Market Revenue (US$ Million), 2020 – 2030
6. North America Bioreactors Market Analysis – Scale
6.1 Overview
6.2 Bioreactors Market Revenue Share, by Scale 2022 & 2030 (%)
6.3 Lab-Scale Production
6.3.1 Overview
6.3.2 Lab-Scale Production Market, Revenue and Forecast to 2030 (US$ Million)
6.4 Pilot-Scale Production
6.4.1 Overview
6.4.2 Pilot-Scale Production Market, Revenue and Forecast to 2030 (US$ Million)
6.5 Full-Scale Productions
6.5.1 Overview
6.5.2 Full-Scale Production Market, Revenue and Forecast to 2030 (US$ Million)
7. North America Bioreactors Market Analysis – Application
7.1 Overview
7.2 Bioreactors Market Revenue Share, by Application 2022 & 2030 (%)
7.3 Microbial Application
7.3.1 Overview
7.3.2 Microbial Application Market, Revenue and Forecast to 2030 (US$ Million)
7.4 Cell Culture Application
7.4.1 Overview
7.4.2 Cell Culture Application Market, Revenue and Forecast to 2030 (US$ Million)
7.5 Others
7.5.1 Overview
7.5.2 Others Market, Revenue and Forecast to 2030 (US$ Million)
8. North America Bioreactors Market Analysis – Technology
8.1 Overview
8.2 Bioreactors Market Revenue Share, by Technology 2022 & 2030 (%)
8.3 Fed-Batch Bioreactors
8.3.1 Overview
8.3.2 Fed-Batch Bioreactors Market, Revenue and Forecast to 2030 (US$ Million)
8.4 Perfusion Bioreactors
8.4.1 Overview
8.4.2 Perfusion Bioreactors Market, Revenue and Forecast to 2030 (US$ Million)
9. North America Bioreactors Market Analysis – End User
9.1 Overview
9.2 Bioreactors Market Revenue Share, by End User 2022 & 2030 (%)
9.3 Biopharma Manufacturers
9.3.1 Overview
9.3.2 Biopharma Manufacturers Market, Revenue and Forecast to 2030 (US$ Million)
9.4 Research and Development Organizations
9.4.1 Overview
9.4.2 Research and Development Organizations Market, Revenue and Forecast to 2030 (US$ Million)
9.5 Contract Manufacturing Organization
9.5.1 Overview
9.5.2 Contract Manufacturing Organization Market, Revenue and Forecast to 2030 (US$ Million)
10. North America Bioreactors Market – by Country Analysis
10.1 North America: Bioreactors Market
10.1.1 North America Bioreactors Market Revenue and Forecasts and Analysis – By Country
10.1.1.1 United States
10.1.1.2 Overview
10.1.1.3 US: Bioreactors Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.3.1 United States Bioreactors Market Breakdown by Scale
10.1.1.3.2 United States Bioreactors Market Breakdown by Application
10.1.1.3.3 United States Bioreactors Market Breakdown by Technology
10.1.1.3.4 United States Bioreactors Market Breakdown by End User
10.1.1.4 Canada
10.1.1.5 Overview
10.1.1.6 Canada: Bioreactors Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.6.1 Canada Bioreactors Market Breakdown by Scale
10.1.1.6.2 Canada Bioreactors Market Breakdown by Application
10.1.1.6.3 Canada Bioreactors Market Breakdown by Technology
10.1.1.6.4 Canada Bioreactors Market Breakdown by End User
10.1.1.7 Mexico
10.1.1.8 Overview
10.1.1.9 Mexico: Bioreactors Market – Revenue and Forecast to 2030 (US$ Million)
10.1.1.9.1 Mexico Bioreactors Market Breakdown by Scale
10.1.1.9.2 Mexico Bioreactors Market Breakdown by Application
10.1.1.9.3 Mexico Bioreactors Market Breakdown by Technology
10.1.1.9.4 Mexico Bioreactors Market Breakdown by End User
11. Bioreactors Market-Industry Landscape
11.1 Overview
11.2 Growth Strategies in the Bioreactors Market
11.3 Inorganic Growth Strategies
11.3.1 Overview
11.4 Organic Growth Strategies
11.4.1 Overview
12. Company Profiles
12.1 PBS Biotech Inc
12.1.1 Key Facts
12.1.2 Business Description
12.1.3 Products and Services
12.1.4 Financial Overview
12.1.5 SWOT Analysis
12.1.6 Key Developments
12.2 General Electric Co
12.2.1 Key Facts
12.2.2 Business Description
12.2.3 Products and Services
12.2.4 Financial Overview
12.2.5 SWOT Analysis
12.2.6 Key Developments
12.3 Merck KGaA
12.3.1 Key Facts
12.3.2 Business Description
12.3.3 Products and Services
12.3.4 Financial Overview
12.3.5 SWOT Analysis
12.3.6 Key Developments
12.4 Thermo Fisher Scientific Inc
12.4.1 Key Facts
12.4.2 Business Description
12.4.3 Products and Services
12.4.4 Financial Overview
12.4.5 SWOT Analysis
12.4.6 Key Developments
12.5 Sartorius AG
12.5.1 Key Facts
12.5.2 Business Description
12.5.3 Products and Services
12.5.4 Financial Overview
12.5.5 SWOT Analysis
12.5.6 Key Developments
12.6 Pall Corp
12.6.1 Key Facts
12.6.2 Business Description
12.6.3 Products and Services
12.6.4 Financial Overview
12.6.5 SWOT Analysis
12.6.6 Key Developments
12.7 Solaris Biotechnology SRL
12.7.1 Key Facts
12.7.2 Business Description
12.7.3 Products and Services
12.7.4 Financial Overview
12.7.5 SWOT Analysis
12.7.6 Key Developments
12.8 Applikon Biotechnology BV
12.8.1 Key Facts
12.8.2 Business Description
12.8.3 Products and Services
12.8.4 Financial Overview
12.8.5 SWOT Analysis
12.8.6 Key Developments
13. Appendix
13.1 About the Research Team
13.2 Glossary of Terms
LIST OF TABLES
Table 1. Bioreactors Market Segmentation
Table 2. United States Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By Scale
Table 3. United States Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By Application
Table 4. United States Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By Technology
Table 5. United States Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By End User
Table 6. Canada Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By Scale
Table 7. Canada Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By Application
Table 8. Canada Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By Technology
Table 9. Canada Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By End User
Table 10. Mexico Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By Scale
Table 11. Mexico Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By Application
Table 12. Mexico Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By Technology
Table 13. Mexico Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn) – By End User
Table 14. Recent Inorganic Growth Strategies in the Bioreactors Market
Table 15. Recent Organic Growth Strategies in the Bioreactors Market
Table 16. Glossary of Terms, Bioreactors Market
LIST OF FIGURES
Figure 1. Bioreactors Market Segmentation, By Country
Figure 2. Impact Analysis of Drivers and Restraints
Figure 3. Bioreactors Market Revenue (US$ Million), 2020 – 2030
Figure 4. Bioreactors Market Revenue Share, by Scale 2022 & 2030 (%)
Figure 5. Lab-Scale Production Market Revenue and Forecasts to 2030 (US$ Million)
Figure 6. Pilot-Scale Production Market Revenue and Forecasts to 2030 (US$ Million)
Figure 7. Full-Scale Production Market Revenue and Forecasts to 2030 (US$ Million)
Figure 8. Bioreactors Market Revenue Share, by Application 2022 & 2030 (%)
Figure 9. Microbial Application Market Revenue and Forecasts to 2030 (US$ Million)
Figure 10. Cell Culture Application Market Revenue and Forecasts to 2030 (US$ Million)
Figure 11. Others Market Revenue and Forecasts to 2030 (US$ Million)
Figure 12. Bioreactors Market Revenue Share, by Technology 2022 & 2030 (%)
Figure 13. Fed-Batch Bioreactors Market Revenue and Forecasts to 2030 (US$ Million)
Figure 14. Perfusion Bioreactors Market Revenue and Forecasts to 2030 (US$ Million)
Figure 15. Bioreactors Market Revenue Share, by End User 2022 & 2030 (%)
Figure 16. Biopharma Manufacturers Market Revenue and Forecasts to 2030 (US$ Million)
Figure 17. Research and Development Organizations Market Revenue and Forecasts to 2030 (US$ Million)
Figure 18. Contract Manufacturing Organization Market Revenue and Forecasts to 2030 (US$ Million)
Figure 19. North America: Bioreactors Market, by Key Country – Revenue (2022) (US$ Million)
Figure 20. North America Bioreactors Market Breakdown by Key Countries, 2022 and 2030 (%)
Figure 21. United States Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn)
Figure 22. Canada Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn)
Figure 23. Mexico Bioreactors Market Revenue and Forecasts to 2030 (US$ Mn)
Figure 24. Growth Strategies in the Bioreactors Market
The List of Companies – North America Bioreactors Market
o PBS Biotech Inc
o General Electric Co
o Merck KGaA
o Thermo Fisher Scientific Inc
o Sartorius AG
o Pall Corp
o Solaris Biotechnology SRL
o Applikon Biotechnology BV
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